世界复合医学2024,Vol.10Issue(3) :176-179.DOI:10.11966/j.issn.2095-994X.2024.10.03.45

消化内镜黏膜下剥离术治疗早期食管癌的效果

Effect of Endoscopic Submucosal Dissection in the Treatment of Early Esophageal Cancer

宫雪娟 宋红伟 王世恒 陈鑫廷
世界复合医学2024,Vol.10Issue(3) :176-179.DOI:10.11966/j.issn.2095-994X.2024.10.03.45

消化内镜黏膜下剥离术治疗早期食管癌的效果

Effect of Endoscopic Submucosal Dissection in the Treatment of Early Esophageal Cancer

宫雪娟 1宋红伟 1王世恒 1陈鑫廷1
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作者信息

  • 1. 吉林省肿瘤医院内镜科,吉林长春 130021
  • 折叠

摘要

目的 分析在早期食管癌患者中应用消化内镜黏膜下剥离术的治疗效果.方法 单纯随机选取2021年4月—2023年5月吉林省肿瘤医院收治的100例早期食管癌患者为研究对象,以随机信封法分为对照组(n=51,行内镜分片黏膜切除术)、观察组(n=49,行消化内镜黏膜下剥离术).对比两组围术期指标、并发症总发生率及病灶切除效果.结果 观察组手术时间(56.47±6.37)min、术后禁食时间(1.98±0.42)d、住院时间(6.94±1.94)d,均短于对照组(70.25±7.36)min、(2.21±0.25)d、(7.94±2.04)d,差异有统计学意义(t=9.994、3.343、2.510,P均<0.05).两组抗生素使用时间、并发症总发生率对比,差异无统计学意义(P均>0.05).观察组病灶整块切除率(93.88%)、病灶治愈性切除率(87.76%)均高于对照组(72.55%、70.59%),差异有统计学意义(χ2=8.057、4.439,P均<0.05).结论 消化内镜黏膜下剥离术治疗早期食管癌,可缩短手术时间、术后禁食时间及住院时间,不会增加并发症发生率,安全性较高,且病灶切除效果更加显著.

Abstract

Objective To analyze the effect of the application of digestive endoscopic submucosal dissec-tion on the effect of lesion resection in the treatment of patients with early esophageal cancer.Methods A total of 100 patients with early esophageal cancer admitted to Jilin Province Cancer Hospital from April 2021 to May 2023 were selected as the study objects.They were divided into the control group(n=51,endoscopic fragmenta-tion mucosal resection)and the observation group(n=49,endoscopic submucosal dissection)by random enve-lope method.Perioperative indexes,total complication rate and lesion resection effect of the two groups were compared.Results The operation time(56.47±6.37)min,postoperative fasting time(1.98±0.42)d and hospi-talization time(6.94±1.94)d in the observation group were shorter than those in the control group(70.25±7.36)min,(2.21±0.25)d,(7.94±2.04)d,and the differences were statistically significant(t=9.994,3.343,2.510,all P<0.05).There was no significant difference in the duration of antibiotic use and total incidence of complications between the two groups(both P>0.05).The whole lesion resection rate(93.88%)and curative le-sion resection rate(87.76%)in observation group were higher than those in control group(72.55%,70.59%),and the differences were statistically significant(χ2=8.057,4.439,both P<0.05).Conclusion Digestive endo-scopic submucosal dissection for the treatment of early esophageal cancer can shorten the operation time,post-operative fasting time and hospitalization time,will not increase the rate of complications,has higher safety,and the effect of lesion resection is more significant.

关键词

早期食管癌/内镜分片黏膜切除术/消化内镜黏膜下剥离术/围术期指标/并发症

Key words

Early esophageal cancer/Endoscopic fractional mucosal resection/Digestive endoscopic submucosal dissection/Perioperative index/Complications

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出版年

2024
世界复合医学

世界复合医学

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