世界复合医学2024,Vol.10Issue(4) :49-53.DOI:10.11966/j.issn.2095-994X.2024.10.04.13

中西医联合方案治疗上呼吸道感染的效果与安全性评价

Efficacy and Safety Evaluation of Integrated Traditional Chinese and Western Medicine in the Treatment of Upper Respiratory Tract Infection

高美丽 王晓鹏 田嘉琦
世界复合医学2024,Vol.10Issue(4) :49-53.DOI:10.11966/j.issn.2095-994X.2024.10.04.13

中西医联合方案治疗上呼吸道感染的效果与安全性评价

Efficacy and Safety Evaluation of Integrated Traditional Chinese and Western Medicine in the Treatment of Upper Respiratory Tract Infection

高美丽 1王晓鹏 1田嘉琦2
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作者信息

  • 1. 北京中医医院顺义医院急诊科,北京 101300
  • 2. 中国中医科学院望京医院心血管内科,北京 100000
  • 折叠

摘要

目的 探讨中西医联合方案治疗上呼吸道感染的临床效果.方法 选取2022年12月—2023年9月北京中医医院顺义医院收治的66例上呼吸道感染患者为研究对象,采用抽签法分为观察组与对照组,各33例.对照组使用奥司他韦、头孢呋辛酯治疗,观察组在对照组治疗的基础上加用银连排毒汤治疗,比较两组的治疗效果.结果 观察组治疗总有效率为 96.97%,高于对照组的78.79%,差异有统计学意义(χ2=5.121,P=0.024).观察组发热、咽喉痛、头痛、咳嗽咳痰和鼻塞流涕症状消失时间均短于对照组,差异有统计学意义(P均<0.05).治疗后,观察组的白细胞介素-10水平高于对照组,降钙素原、C反应蛋白水平低于对照组,差异有统计学意义(P均<0.05).治疗后,观察组免疫球蛋白A、免疫球蛋白G、免疫球蛋白M水平高于对照组,差异有统计学意义(P均<0.05).两组不良反应发生率比较,差异无统计学意义(P>0.05).结论 在上呼吸道感染的治疗中,常规的西医治疗方法虽然能够缓解症状,但在停止用药后复发的可能性较高,加入银连排毒汤能够更好地改善患者的免疫应答和炎性反应,进而取得更好的治疗效果.

Abstract

Objective To investigate the clinical effect of integrated traditional Chinese and Western Medi-cine in the treatment of upper respiratory tract infection.Methods A total of 66 patients with upper respiratory tract infection who received treatment in the Shunyi Hospital of Beijing Traditional Chinese Medicine Hospital from December 2022 to September 2023 were selected as the study objects,and they were divided into observa-tion group and control group by lottery method,with 33 cases in each group.The control group was treated with oseltamivir and cefuroxime axetil,and the observation group was treated with Yinlian detoxification decoction on the basis of the control group.The therapeutic effect of the two groups was compared.Results The total effec-tive rate of the observation group was 96.97%,higher than 78.79%of the control group,and the difference was statistically significant(χ2=5.121,P=0.024).The disappearance time of fever,sore throat,headache,cough and phlegm and nasal obstruction in observation group were shorter than those in control group,and the differences were statistically significant(all P<0.05).After treatment,the interleukin-10 level in the observation group was higher than that in the control group,while procalcitonin and C-reactive protein levels were lower than those in the control group,and the differences were statistically significant(all P<0.05).After treatment,the levels of im-munoglobulin A,immunoglobulin G and immunoglobulin M in the observation group were higher than those in the control group,and the differences were statistically significant(all P<0.05).There was no significant differ-ence in the incidence of adverse reactions between the two groups(P>0.05).Conclusion In the treatment of up-per respiratory tract infection,although conventional Western medicine treatment can alleviate symptoms,it is highly likely to relapse after stopping medication.Adding Yinlian detoxification decoction can better improve the immune response and inflammatory response of patients and thus achieve better therapeutic effect.

关键词

上呼吸道感染/银连排毒汤/免疫应答/炎性反应

Key words

Upper respiratory tract infection/Yinlian detoxification decoction/Immune response/In-flammatory response

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出版年

2024
世界复合医学

世界复合医学

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