Objective To analyze the curative effect of Shexiang Baoxin pill combined with Tirofiban on acute myocardial infarction(AMI)and the influence of serum intelectin-1(ITLN-1)and soluble intercelluar ad-hesion molecule 1(sICAM-1).Methods The clinical data of ninety patients with AMI admitted to Gansu Prov-ince Third People's Hospital from July 2021 to July 2023 were retrospectively selected,and they were divided into control group(n=45,treated with tirofiban)and observation group(n=45,treated with Shexiang Baoxin pill combined with tirofiban)according to different medication methods.The therapeutic effect,serum ITLN-1,sI-CAM-1 levels,cardiac function[left ventricular ejection fraction(LVEF),left ventricular systolic diameter(LVESD),left ventricular end diastolic diameter(LVEDD)]levels before and after treatment of the two groups were compared.Results The total effective rate of the observation group(95.56%)was higher than that of the control group(82.22%),and the difference was statistically significant(χ2=4.050,P<0.05).There were no sig-nificant differences in serum ITLN-1,sICAM-1 and related cardiac function indexes(LVEF,LVESD,LVEDD)between the two groups before treatment(all P>0.05).After treatment,ITLN-1 was higher and sICAM-1 level was lower in observation group than those in control group,and the differences were statistically significant(both P<0.05).After treatment,LVEF in observation group was higher than that in control group,LVEDD and LVESD were lower than that in control group,and the differences were statistically significant(all P<0.05).Conclusion Shexiang Baoxin pill combined with tirofiban has significant curative effect in the treatment of AMI,which can significantly increase the level of ITLN-1,reduce the level of sICAM-1 and improve the car-diac function of patients.
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