世界复合医学2024,Vol.10Issue(4) :107-110.DOI:10.11966/j.issn.2095-994X.2024.10.04.27

胃康灵胶囊联合雷贝拉唑治疗胃溃疡的临床效果

Clinical Effect of Weikangling Capsule Combined with Rabeprazole on Gastric Ulcer

王平 边艳艳 景利成
世界复合医学2024,Vol.10Issue(4) :107-110.DOI:10.11966/j.issn.2095-994X.2024.10.04.27

胃康灵胶囊联合雷贝拉唑治疗胃溃疡的临床效果

Clinical Effect of Weikangling Capsule Combined with Rabeprazole on Gastric Ulcer

王平 1边艳艳 1景利成1
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作者信息

  • 1. 临洮县人民医院药剂科,甘肃 定西 730500
  • 折叠

摘要

目的 探究对胃溃疡的患者采用雷贝拉唑联合胃康灵胶囊治疗的临床效果.方法 回顾性选取2020年10月—2022年8月临洮县人民医院收治的125例胃溃疡患者的临床资料.根据治疗方法的不同将患者分为两组,研究组(n=63)采用雷贝拉唑联合胃康灵胶囊治疗,对照组(n=62)采用雷贝拉唑治疗.对比两组治疗效果、不良反应、炎症因子指标以及视觉模拟评分法(Visual Analogue Scale,VAS)评分.结果 研究组治疗总有效率(95.24%)高于对照组(83.87%),差异有统计学意义(χ2=4.333,P<0.05).两组不良反应总发生率对比(9.52%vs 12.90%),差异无统计学意义(χ2=0.359,P>0.05).治疗后两组白细胞介素-6、肿瘤坏死因子-α、白细胞介素-8及VAS评分较治疗前均降低,且研究组均低于对照组,差异有统计学意义(P均<0.05).结论 应用雷贝拉唑联合胃康灵胶囊治疗胃溃疡具有明显的效果.

Abstract

Objective To explore the effect of rabeprazole combined with Weikangling capsule on patients with gastric ulcer.Methods The clinical data of one hundred and twenty-five patients with gastric ulcer admit-ted from October 2020 to August 2022 in Lintao County People's Hospital were retrospectively selected,and the patients were divided into two groups according to different treatment method.The study group(n=63)was treated with rabeprazole combined with Weikangling capsule,and the control group(n=62)was treated with ra-beprazole.Treatment effect,adverse reactions,inflammatory factors,and Visual Analogue Scale(VAS)score of two groups were compared.Results The total effective rate of the study group(95.24%)was higher than that of the control group(83.87%),and the difference was statistically significant(χ2=4.333,P<0.05).There was no sig-nificant difference in the total incidence of adverse reactions between the two groups(9.52%vs 12.90%)(χ2=0.359,P>0.05).After treatment,the levels of interleukin-6,tumor necrosis factor-α,interleukin-8 and VAS scores in two groups were lower than those before treatment,and the study group were lower than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion The combined applica-tion of rabeprazole and Weikangling capsule has obvious effect in the treatmentof gastric ulcer.

关键词

雷贝拉唑/胃康灵胶囊/胃溃疡/治疗效果/不良反应/炎症因子

Key words

Rabeprazole/Weikangling capsule/Gastric ulcer/Therapeutic effect/Adverse reactions/In-flammatory factor

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出版年

2024
世界复合医学

世界复合医学

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