世界复合医学2024,Vol.10Issue(4) :111-114.DOI:10.11966/j.issn.2095-994X.2024.10.04.28

通心络胶囊与酒石酸美托洛尔联合治疗冠心病心绞痛的效果研究

Effect of Tongxinluo Capsule Combined with Metoprolol Tartrate in the Treatment of Coronary Heart Disease and Angina Pectoris

罗华龙 赵娜 周之征
世界复合医学2024,Vol.10Issue(4) :111-114.DOI:10.11966/j.issn.2095-994X.2024.10.04.28

通心络胶囊与酒石酸美托洛尔联合治疗冠心病心绞痛的效果研究

Effect of Tongxinluo Capsule Combined with Metoprolol Tartrate in the Treatment of Coronary Heart Disease and Angina Pectoris

罗华龙 1赵娜 2周之征1
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作者信息

  • 1. 商河县人民医院心内科,山东 济南 251600
  • 2. 济南市第七人民医院心内科,山东 济南 250101
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摘要

目的 分析通心络胶囊与酒石酸美托洛尔(metoprolol tartrate,MT)联合治疗冠心病心绞痛的效果.方法 选取2021年10月—2023年9月商河县人民医院收治的198例冠心病心绞痛患者为研究对象,参照随机数表法分为两组,各99例.对照组采用MT治疗,研究组在对照组治疗的基础上联合通心络胶囊治疗.比较两组临床疗效、心绞痛症状发作情况及硝酸甘油用量、不良反应发生率.结果 研究组治疗总有效率为95.86%,高于对照组的86.87%,差异有统计学意义(χ2=6.111,P<0.05).治疗8周后,研究组心绞痛症状每周发作频率、每次持续时间及硝酸甘油用量均少于对照组,差异有统计学意义(P均<0.05).两组不良反应发生率比较,差异无统计学意义(P>0.05).结论 MT联合通心络胶囊治疗冠心病心绞痛效果确切,能够有效改善患者的症状,安全性佳.

Abstract

Objective To analyze the efficacy of the combination of Tongtxinluo capsule and metoprolol tar-trate(MT)in the treatment of angina pectoris(AP)in coronary heart disease(CHD).Method A total of 198 CHD-AP patients admitted to the Department of Cardiology of Shanghe County People's Hospital from October 2021 to September 2023 were selected as the study objects and divided into two groups with 99 cases each ac-cording to random number table method.The control group was treated with MT,and the study group was treated with Tongxinluo capsule on the basis of the control group.The clinical efficacy,incidence of AP symp-toms,nitroglycerin dosage,and incidence of adverse reactions were compared between the two groups.Results The total effective rate of the study group was 95.86%,which was higher than 86.87%of the control group,the difference was statistically significant(χ2=6.111,P<0.05).After 8 weeks of treatment,the frequency and dura-tion of AP symptoms per week and the dosage of nitroglycerin in the study group were less than those in the con-trol group,and the differences were statistically significant(all P<0.05).There was no statistically significant dif-ference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion MT combined with Tongxinluo capsule is effective in the treatment of CHD-AP,which can effectively improve the symptoms of pa-tients with good safety.

关键词

通心络胶囊/酒石酸美托洛尔/冠心病/心绞痛

Key words

Tongxinluo Capsule/Metoprolol tartrate/Coronary heart disease/Angina pectoris

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出版年

2024
世界复合医学

世界复合医学

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