世界复合医学2024,Vol.10Issue(5) :30-34.DOI:10.11966/j.issn.2095-994X.2024.10.05.08

鼻内镜术后辅助应用香菊胶囊治疗慢性鼻窦炎伴鼻息肉的疗效分析

Efficacy of Adjunctive Application of Xiangju Capsules after Nasal Endoscopy in the Treatment of Chronic Rhinosinusitis with Nasal Polyps

崔学英 宋云红
世界复合医学2024,Vol.10Issue(5) :30-34.DOI:10.11966/j.issn.2095-994X.2024.10.05.08

鼻内镜术后辅助应用香菊胶囊治疗慢性鼻窦炎伴鼻息肉的疗效分析

Efficacy of Adjunctive Application of Xiangju Capsules after Nasal Endoscopy in the Treatment of Chronic Rhinosinusitis with Nasal Polyps

崔学英 1宋云红1
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作者信息

  • 1. 山东省济南市商河县人民医院耳鼻喉科,山东 济南 251600
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摘要

目的 探讨鼻内镜术后辅助应用香菊胶囊治疗慢性鼻窦炎伴鼻息肉的效果.方法 回顾性选取2021年5月—2022年6月商河县人民医院收治的86例慢性鼻窦炎伴鼻息肉患者的临床资料,按不同治疗方法分为两组,各43例.对照组予以鼻内镜手术治疗,研究组在对照组基础上辅助应用香菊胶囊治疗.比较两组的临床疗效、鼻腔通气功能指标、嗅觉功能评分、鼻内镜Lund-Kennedy评分、炎症指标水平及复发率.结果 研究组的治疗总有效率为95.35%(41/43),高于对照组的81.40%(35/43),差异有统计学意义(χ2=4.074,P<0.05).治疗后,研究组的鼻腔容积、鼻气道阻力、鼻腔最小横截面积等鼻腔通气功能指标改善程度、白细胞介素-2、白细胞介素-6、C反应蛋白水平、嗅觉功能以及鼻内镜Lund-Kennedy评分明显优于对照组,差异有统计学意义(P均<0.05).研究组复发率低于对照组,差异有统计学意义(P<0.05).结论 鼻内镜术后辅助应用香菊胶囊治疗慢性鼻窦炎伴鼻息肉能够提高临床疗效,改善鼻腔通气功能和嗅觉功能,减轻鼻部炎症反应,降低复发率.

Abstract

Objective To explore the therapeutic effect of adjunctive application of Xiangju Capsule on pa-tients with chronic rhinosinusitis with nasal polyps after nasal endoscopy.Methods The clinical data of 86 pa-tients with chronic rhinosinusitis with nasal polyps admitted to Shanghe County People's Hospital from May 2021 to June 2022 were retrospectively selected and divided into two groups of 43 patients each according to dif-ferent treatment methods.The control group was treated with nasal endoscopic surgery,and the study group was treated with the adjunctive application of Xiangju Capsule on the basis of the control group.The clinical effi-cacy,nasal ventilation function indexes,olfactory function score,nasal endoscopic Lund-Kennedy score,in-flammation index level and recurrence rate of the two groups were compared.Results The total effective rate of treatment in the study group was 95.35%(41/43),whic was higher than 81.40%(35/43)in the control group,and the difference was statistically significant(χ2=4.074,P<0.05).After treatment,the degree of improvement of nasal ventilation function indexes such as nasal cavity volume,nasal airway resistance,minimal cross-sectional area,interleukin-2,interleukin-6,C-reactive protein levels,as well as olfactory function and the na-sal endoscopic Lund-Kennedy score of the study group were significantly better than that of the control group,and the differences were statistically significant(all P<0.05).The recurrence rate of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Adjunctive application of Xiangju Capsule in the treatment of chronic rhinosinusitis with nasal polyps after nasal endoscopy can improve the clinical efficacy,improve the nasal ventilation function and olfactory function,reduce the in-flammatory response of the nose,and reduce the recurrence rate.

关键词

鼻内镜术/香菊胶囊/慢性鼻窦炎/鼻息肉/临床疗效

Key words

Nasal endoscopy/Xiangju Capsule/Chronic rhinosinusitis/Nasal polyps/Clinical efficacy

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出版年

2024
世界复合医学

世界复合医学

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