世界复合医学2024,Vol.10Issue(5) :85-88.DOI:10.11966/j.issn.2095-994X.2024.10.05.21

参麦注射液与小剂量糖皮质激素联合治疗老年重症肺炎的效果分析

Effect of Shenmai Injection Combined with Low-dose Glucocorticosteroid on Senile Severe Pneumonia

陶祥丹 宋雪薇 李得震
世界复合医学2024,Vol.10Issue(5) :85-88.DOI:10.11966/j.issn.2095-994X.2024.10.05.21

参麦注射液与小剂量糖皮质激素联合治疗老年重症肺炎的效果分析

Effect of Shenmai Injection Combined with Low-dose Glucocorticosteroid on Senile Severe Pneumonia

陶祥丹 1宋雪薇 1李得震1
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作者信息

  • 1. 曹县人民医院呼吸与危重症医学科,山东 菏泽 274400
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摘要

目的 分析老年重症肺炎患者采用参麦注射液与小剂量糖皮质激素联合治疗的效果.方法 选取2022年8月—2023年7月曹县人民医院收治的96例老年重症肺炎患者为研究对象,按照治疗方法不同将患者分为两组,各48例.对照组采用小剂量糖皮质激素治疗,研究组在对照组基础上联用参麦注射液.比较两组疗效、C反应蛋白、降钙素原水平、不良反应发生率.结果 研究治疗有效率为95.83%(46/48),高于对照组的81.25%(39/48),差异有统计学意义(χ2=5.031,P<0.05).治疗7 d后,与对照组相比,研究组C反应蛋白、降钙素原水平更低,差异有统计学意义(P均<0.05).两组不良反应发生率比较,差异无统计学意义(P>0.05).结论 老年重症肺炎患者采用参麦注射液联合小剂量糖皮质激素治疗能够取得满意的临床疗效,降低炎症因子水平,具有临床应用价值.

Abstract

Objective To analyze the effect of Shenmai Injection combined with low-dose glucocorticoste-roid on senile patients with severe pneumonia.Methods A total of ninety-six elderly severecase pneumonia pa-tients admitted to Caoxian People's Hospital from August 2022 to July 2023 were selected as the study objects the patients were divided into two groups with forty-eight patients in each group according to different treatment method.The control group was treated with low-dose glucocorticosteroid,and the study group was treated with Shenmai injection.The efficacy,C-reactive protein,procalcitonin levels and the incidence of adverse reactions were compared between the two groups.Results The effective rate of the study treatment was 95.83%(46/48),higher than 81.25%(39/48)of the control group,and the difference was statistically significant(χ2=5.031,P<0.05).After 7 days of treatment,the levels of C-reactive protein and procalcitonin in the study group were lower than those in the control group,and the differences were statistically significant(both P<0.05).There was no sig-nificant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Shenmai Injection combined with low-dose glucocorticosteroid in elderly severe pneumonia patients can achieve satis-factory clinical effect and reduce the level of inflammatory factors,which has clinical application value.

关键词

参麦注射液/糖皮质激素/老年/重症肺炎

Key words

Shenmai Injection/Glucocorticosteroid/Elderly/Severe pneumonia

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出版年

2024
世界复合医学

世界复合医学

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