世界复合医学2024,Vol.10Issue(5) :129-132.DOI:10.11966/j.issn.2095-994X.2024.10.05.32

纤维支气管镜辅助治疗重症呼吸机相关性肺炎的临床价值

Clinical Value of Fiberoptic Bronchoscopy-assisted Treatment of Severe Ventilator-associated Pneumonia

刘力新 郭园园 刘方建
世界复合医学2024,Vol.10Issue(5) :129-132.DOI:10.11966/j.issn.2095-994X.2024.10.05.32

纤维支气管镜辅助治疗重症呼吸机相关性肺炎的临床价值

Clinical Value of Fiberoptic Bronchoscopy-assisted Treatment of Severe Ventilator-associated Pneumonia

刘力新 1郭园园 2刘方建3
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作者信息

  • 1. 巨野县人民医院呼吸内科,山东 菏泽 274900
  • 2. 巨野县人民医院创伤小儿骨科,山东 菏泽 274900
  • 3. 巨野县人民医院肛肠外科,山东 菏泽 274900
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摘要

目的 分析重症呼吸机相关性肺炎(ventilator associated pneumonia,VAP)实施纤维支气管镜辅助治疗的价值.方法 选取2022年4月—2023年3月巨野县人民医院收治的78例VAP患者为研究对象,根据不同治疗方式分为对照组与研究组,各39例.对照组行传统治疗,研究组在对照组基础上辅以纤维支气管镜治疗.比较两组炎症因子(白细胞介素-8,降钙素原、C反应蛋白)、呼吸力学指标(呼吸做功、气道阻力、气道峰压)、恢复时间(炎症控制时间、机械通气时间、ICU治疗时间、住院时间)及临床疗效.结果 治疗后,两组炎症因子水平均下降,且研究组低于对照组,差异有统计学意义(P均<0.05).治疗后,两组呼吸力学指标均下降,且研究组低于对照组,差异有统计学意义(P均<0.05).研究组患者恢复时间和住院时间均短于对照组,差异有统计学意义(P均<0.05).研究组治疗总有效率为97.44%(38/39),高于对照组的84.62%(33/39),差异有统计学意义(χ2=3.924,P=0.048).结论 纤维支气管镜的效果好,能缩短VAP患者恢复时间,降低炎症因子水平,改善呼吸力学状态.

Abstract

Objective To analyze the value of fiberoptic bronchoscopy-assisted treatment for severe ventilator-associated pneumonia(VAP).Methods Seventy-eight patients with VAP admitted to Juye County People's Hospital from April 2022 to March 2023 were selected for the study,and they were divided into a con-trol group and a study group of 39 cases each according to different treatment methods.The control group was treated with traditional therapy,and the study group was supplemented with fiberoptic bronchoscopy on the ba-sis of the control group.The inflammatory factors(interleukin-8,procalcitonin,C-reactive protein),respiratory mechanics indexes(respiratory work,airway resistance,airway peak pressure),recovery time(inflammation con-trol time,mechanical ventilation time,ICU treatment time,discharge time)and clinical efficacy were compared between the two groups.Results After treatment,the levels of inflammatory factor decreased in both groups,and the study group were lower than the control group,the differences were statistically significant(all P<0.05).Af-ter treatment,the respiratory mechanics indexes of the two groups decreased and the study group were lower than the control group,and the differences were statistically significant(all P<0.05).The recovery time and hos-pitalization time of patients in the study group were shorter than those of the control group,and the differences were statistically significant(both P<0.05).The total effective rate of the study group was 97.44%(38/39),higher than 84.62%(33/39)in the control group,and the difference was statistically significant(χ2=3.924,P=0.048).Conclusion Fiberoptic bronchoscopy is effective in shortening the recovery time of VAP,reducing the level of inflammatory factors,and improving the state of respiratory mechanics.

关键词

重症呼吸机相关性肺炎/有效性/安全性/纤维支气管镜

Key words

Severe ventilator-associated pneumonia/Effectiveness/Safety/Fiberoptic bronchoscopy

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出版年

2024
世界复合医学

世界复合医学

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