首页|探讨自血疗法对维持性血液透析患者生存质量的影响

探讨自血疗法对维持性血液透析患者生存质量的影响

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目的 探讨自血疗法对维持性血液透析患者生存质量的影响.方法 选取2021年1月—2022年12月在茂名市中医院行维持性血液透析的88例患者为研究对象,按照不同治疗方法分为两组,每组44例.对照组采用常规血液透析治疗,观察组在对照组的基础上采用自血疗法治疗.比较两组T淋巴细胞亚群水平、炎症相关指标、生存质量评分、肾功能指标、不良反应发生情况及治疗效果.结果 治疗后,观察组CD3+和CD4+水平高于对照组,CD8+水平低于对照组,差异有统计学意义(P均<0.05).治疗后,观察组高敏C反应蛋白、白细胞介素-6、肿瘤坏死因子-α水平低于对照组,差异有统计学意义(P均<0.05).治疗后,观察组生存质量评分高于对照组,差异有统计学意义(P均<0.05).治疗后,观察组血尿素氮、肌酐水平低于对照组,白蛋白和血红蛋白水平高于对照组,差异有统计学意义(P均<0.05).观察组治疗总有效率为100.00%(44/44),高于对照组的84.09%(37/44),差异有统计学意义(χ2=7.605,P<0.05).观察组不良反应总发生率低于对照组,差异有统计学意义(P<0.05).结论 对于维持性血液透析患者采用自血疗法能够显著改善患者的免疫功能、微炎症状态、生存质量及肾功能,降低不良反应发生率以及提高治疗效果.
Effect of Autohemotherapy on the Quality of Life of Patients with Maintenance Hemodialysis
Objective To explore the influence of autohemtherapy on the quality of life of maintenance he-modialysis patients.Methods A total of 88 patients who underwent maintenance hemodialysis in Maoming Hos-pital of Traditional Chinese Medicine from January 2021 to December 2022 were selected as the research ob-jects.They were divided into two groups according to the differentment treatment method,with 44 cases in each group.The control group was treated with conventional hemodialysis,and the observation group was treated with autohemotherapy on the basis of the control group.T lymphocyte subsets levels,related indicators of inflamma-tion,quality of life score,kidney index,adverse reaction occurrence and treatment effect of two groups were compared.Results After treatment,the levels of CD3+and CD4+in the observation group were higher than those in the control group,and the level of CD8+was lower than that in the control group,and the differences were sta-tistically significant(all P<0.05).After treatment,the levels of hypersensitive C-reactive protein,interleukin-6 and tumor necrosis factor-α in the observation group were lower than those in the control group,and the differ-ences were statistically significant(all P<0.05).After treatment,the quality of life scores of the observation group were higher than that of the control group,and the differences were statistically significant(all P<0.05).After treatment,the levels of blood urea nitrogen and creatinine in the observation group were lower than those in the control group,and the levels of albumin and hemoglobin were higher than those in the control group,and the differences were statistically significant(all P<0.05).The total effective rate of the observation group 100.00%(44/44),which was higher than 84.09%(37/44)of the control group,and the difference was statisti-cally significant(χ2=7.605,P<0.05).The total incidence of adverse reactions in the observation group was lower than in the control group,and the difference was statistically significant(P<0.05).Conclusion For maintenance hemodialysis patients,autohemotherapy can significantly improve their immune function,microinflammatory status,quality of life and renal function,reduce the incidence of adverse reactions in patients and improve the therapeutic effect.

Maintenance hemodialysisAutohemotherapyQuality of life

文朝晖、杨禄颜、魏涛、曾明源、黄亚羡、陈福聪

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茂名市中医院肾内科,广东 茂名 525000

维持性血液透析 自血疗法 生存质量

广东省中医药局科研项目

20221454

2024

世界复合医学

世界复合医学

ISSN:
年,卷(期):2024.10(6)
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