Effect of Ginkgo Diterpene Lactone on Serum slCAM-1,PTX-3 and ET-1 in Patients with Acute Cerebral Infarction
Objective To analyze the effects of ginkgo diterpene lactone on serum soluble intercellular ad-hesion molecule 1(slCAM-1),recombinant pentraxin 3(PTX-3)and Endothelin-1(ET-1)in patients with acute cerebral infarction.Methods A total of 76 patients with acute cerebral infarction admitted to Caoxian People's Hospital from March 2022 to March 2023 were selected as the study objects.According to different treatment methods,they were divided into control group(conventional Western medicine treatment)and obser-vation group(conventional Western medicine+ginkgo diterpene lactone treatment),with 38 cases in each group.The levels of serum slCAM-1,PTX-3 and ET-1,neurological impairment,plaque stability were compared be-tween the two groups.Results After treatment,the levels of slCAM-1,PTX-3 and ET-1 in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).After treatment,the score of National Institutes of Health Stroke Scale of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).The plaque stability of the ob-servation group was 92.11%(35/38),which was higher than 73.68%(28/38)of the control group,and the differ-ence was statistically significant(χ2=4.547,P<0.05).Conclusion In the treatment of acute cerebral infarction,ginkgo diterpene lactone can effectively regulate the levels of slCAM-1,PTX-3 and ET-1.
NETL
NSTL
万方数据
