首页|保妇康栓联合干扰素治疗HPV感染的有效性评估

保妇康栓联合干扰素治疗HPV感染的有效性评估

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目的 探讨保妇康栓联合干扰素治疗人乳头瘤病毒(human papilloma virus,HPV)感染的临床效果.方法 选取2022年11月—2023年11月巨野妇幼保健院收治的50例HPV感染患者为研究对象,按照不同治疗方法分为对照组(25例,接受干扰素治疗)、研究组(25例,接受保妇康栓+干扰素治疗),比较两组治疗效果、人乳头瘤病毒-脱氧核糖核酸水平及炎症因子水平.结果 研究组治疗总有效率为96.00%(24/25),高于对照组的72.00%(18/25),差异有统计学意义(χ2=5.357,P=0.021).治疗后,研究组人乳头瘤病毒-脱氧核糖核酸水平、转化生长因子β1、白细胞介素-6以及肿瘤坏死因子-α水平低于对照组,差异有统计学意义(P均<0.05).结论 对于HPV感染患者,采取积极的保妇康栓联合干扰素疗法能控制疾病的进一步发展,对于提高预后效果可起到关键的影响,降低患者人乳头瘤病毒-脱氧核糖核酸水平以及炎性因子指标,提升治疗效果.
Effectiveness of Baofukang Suppository Combined with Interferon in the Treatment of HPV In-fection
Objective To analyze the actual outcome of the treatment of human papilloma virus(HPV)in-fection by Baofukang Suppository and interferon.Methods A total of 50 patients with HPV infection admitted to Juye Maternal and Child Health Hospital from November 2022 to November 2023 were selected as the research objects.They were divided into control group(25 cases,treated with single interferon)and study group(25 cases,treated with Baofukang suppository+interferon)according to different treatment method.The therapeutic effects the levels of human papilloma virus-DNA and inflammatory cytokines of the two groups were compared.Results The total effective rate of treatment in the study group was 96.00%(24/25),which was higher than 72.00%(18/25)in the control group,and the difference was statistically significant(χ2=5.357,P=0.021).After treatment,the levels human papilloma virus-DNA,transforming growth factor β1,interleukin-6 and tumor ne-crosis factor-α in the study group were lower than those in the control group,and the differences were statisti-cally significant(all P<0.05).Conclusion For patients with HPV infection,taking active Baofukang Suppository combined with interferon therapy and controlling the further development of the disease plays a key role in im-proving the prognostic effect,which can reduce the level of patients'Human papilloma virus-DNA and inflam-matory factor indexes,improve the therapeutic effect.

Baofukang SuppositoryInterferonHuman papilloma virus infectionInflammatory factorsHuman papilloma virus-DNA level

张蕾、田洪涛、潘瑞芹

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巨野妇幼保健院,山东 菏泽 274900

菏泽市立医院,山东 菏泽 274900

菏泽市妇幼保健院,山东 菏泽 274900

保妇康栓 干扰素 人乳头瘤病毒感染 炎性因子 人乳头瘤病毒-脱氧核糖核酸水平

2024

世界复合医学

世界复合医学

ISSN:
年,卷(期):2024.10(6)
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