Wood carbon fraction(CF),representing the proportion of carbon in wood biomass,is critical for accurately quantifying forest carbon stocks.Recent studies have quantified wood CF variations across different biomes,taxonomic groups(conifers vs.broadleaves),species,organs,tissue types,and even within individual growth rings.The prevailing use of a generalized CF value(50%)may lead to potential biases in calculating forest carbon storage.This paper reviews major advancements in the study of wood CF variability and discusses the developments in assessment methods,multi-scale research,and database construction for wood CF,aiming to enhance the scientific application of wood CF in forest carbon stock assessments of spatial,temporal,and taxonomic characteristics.