The rice leaf roller,stem borer,and rice planthopper are the main pests and also are a first-class pest in China,with an occurrence of 48 million ha in 2022.The main insecticides,such as diamide,neonicotinoid,avermectin,and meta-diamide&isooxazoline were using to control these rice pests.The pesticide resistance,environmental and ecological safety,and aircraft spraying are the main challenges about these insecticides.For these challenges,we should persist in principle of prevention first and providing comprehensive control,and use insecticide scientific and rational.This article takes the creation of the insecticide cyproflanilide as an example to explore solutions for rice resistance to the stem borer,and providing reference for the innovation of green pesticides.