In order to prepare pyroxasulfone 40%SC with excellent performance,the wetting dispersant and thickener were screened to determine the optimal formulation:40%pyroxasulfone,1.0%polycarboxylate,1.5%polyarylphenol polyether modified product,3.0%composite dispersant,0.2%xanthan gum,4.0%ethylene glycol,0.3%BIT,0.5%silicone defoaming agent,water up to 100%.The suspension rates is higher than 95%and decomposition rates is less than 1%after cold and hot storage.The dispersion is excellent,the water separation rate is low,and other indicators also met the SC standards.Field trials have shown that this product has a weed control effect of over 92%in wheat fields and is highly safe for wheat.