Chordotonal organs are proprioceptive and mechanosensory organs unique to invertebrates.Due to the transient receptor potential vanilloid subtype(TRPV)channels formed by the co-expression of Nanchung and Inactive genes only existing in the chordotonal organ neurons of certain specific insects,they have become an ideal target for the development of modern insecticides.As insecticides that act directly or indirectly on the TRPV channels of target pest chordotonal organs,pymetrozine,pyrifluquinazon,afidopyropen,flonicamid,flumetnicam and dimpropyridaz have unique chemical structures,action mechanisms and excellent safety.They have outstanding biological activities or control effects on piercing-sucking mouthpart insects and the viruses they mediate and transmit,and are suitable for integrated pest control and resistance management.This article introduces the structure,function and characteristics of chordotonal organs and their TRPV channels,and summarizes the synthesis routes,biological activities,action mechanisms,resistance,safety and formulation applications of insecticides targeting this receptor,in order to promote the research,development and application of this class of target insecticides.
关键词
弦音器TRPV通道/杀虫剂/作用机制/生物活性/抗性
Key words
TRPV channels in chordotonal organs/insecticide/action mechanism/biological activity/resistance
维普
万方数据