焦虑障碍患者焦虑情绪与睡眠结构的相关性研究
Correlation between Anxiety and Sleep Structure in Patients with Anxiety Disorders
吴乃付1
作者信息
- 1. 安徽省滁州市第二人民医院睡眠医学科,滁州,239000
- 折叠
摘要
目的:探讨焦虑障碍患者焦虑情绪与睡眠结构之间的相关性.方法:选取2020 年8 月至2023 年 11 月安徽省滁州市第二人民医院睡眠医学科住院治疗的焦虑障碍患者 80 例作为研究对象,均接受多导睡眠监测(PSG).将睡眠效率(SE)≤85%的患者纳为低睡眠效率组(LSE组,n =57),将SE＞85%的患者纳为正常睡眠效率组(NSE组,n =23).采用汉密尔顿焦虑量表(HAMA)评估患者焦虑情绪.采用χ2 检验及独立样本t检验比较2 组患者的一般人口学资料及睡眠结构参数.采用偏相关分析检验焦虑障碍患者睡眠结构与焦虑情绪的相关性.结果:NSE组平均年龄低于LSE 组(P＜0.05),2 组在性别、体质量指数(BMI)、受教育年限、病程方面差异均无统计学意义(均P＞0.05).2 组HAMA评分差异无统计学意义(P＞0.05).LSE组睡眠潜伏期、N1 潜伏期和N2 潜伏期显著长于NSE组,LSE组的N2 持续时间、非快速眼动睡眠(NREM)持续时间均显著低于NSE组(P＜0.05).偏相关分析结果显示,LSE组焦虑情绪与N2 持续时间呈显著正相关(P＜0.05),与N3 期持续时间呈负相关(P＜0.01).在NSE组中未发现上述结果.结论:焦虑障碍伴低睡眠效率患者的深睡眠时长与焦虑情绪呈显著负相关,良好的睡眠质量可能有助于改善焦虑障碍患者焦虑情绪.
Abstract
Objective:To explore the correlation between anxiety and sleep structure in patients with anxiety disorders.Methods:A total of 80 patients with anxiety disorders who were hospitalized in Chuzhou Second People's Hospital from August 2020 to No-vember 2023 were included,and all of them received Overnight polysomnography(PSG).Patients with sleep efficiency(SE)≤85%were categorized into the low sleep efficiency group(LSE group,n =57),and the rest were categorized into the normal sleep efficiency group(NSE group,n =23).The Hamilton Anxiety Scale(HAMA)was used to assess anxiety symptoms in all pa-tients.The χ2 test and independent samples t-test were used to compare the general demographic information and sleep structure parameters of the two groups.Partial correlation analysis was used to examine the correlation between sleep structure and anxiety in patients with anxiety disorders Results:The mean age of the NSE group was lower than that of the LSE group(P＜0.05),and there was no statistically significant difference between the two groups in terms of gender,body mass index(BMI),years of educa-tion,duration of disease and HAMA score(P＞0.05).Sleep latency,N1 latency and N2 latency in the LSE group were signifi-cantly longer than those in the NSE group,and N2 duration and NREM duration in the LSE group were significantly lower than those in the NSE group(P＜0.05).The results of partial correlation analysis showed that anxiety in the LSE group was signifi-cantly positively correlated with N2 duration(P＜0.05)and negatively correlated with N3 duration(P＜0.01).These results were not found in the NSE group.Conclusion:Deep sleep duration is negatively correlated with anxiety symptoms in patients with anxiety disorders with low sleep efficiency,and good sleep quality may help improve anxiety symptoms in patients with anxiety dis-orders.
关键词
睡眠结构/焦虑障碍/整夜多导睡眠监测Key words
Sleep structure/Anxiety disorders/Overnight polysomnography引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据