The therapeutic Effect of Low-frequency Repetitive Transcranial Magnetic Stimulation Combined with Antidepressants on Elderly Patients with Chronic Insomnia and Depression,and Its Impact on Sleep Quality
The therapeutic Effect of Low-frequency Repetitive Transcranial Magnetic Stimulation Combined with Antidepressants on Elderly Patients with Chronic Insomnia and Depression,and Its Impact on Sleep Quality
Objective:To analyze the efficacy of low-frequency repetitive transcranial magnetic stimulation combined with antide-pressants in the treatment of elderly patients with chronic insomnia and depression,and its impact on sleep quality.Methods:A total of 66 elderly patients with chronic insomnia and depression admitted to the 909th Hospital of the Joint Logistics Support Force from January 2019 to January 2022 were selected as the study subjects.They were randomly divided into an observation group(n=33)and a control group(n=33)using a random number table method.The control group received routine antidepres-sant treatment intervention,while the observation group received low-frequency repetitive transcranial magnetic stimulation com-bined with antidepressant treatment on the basis of the control group.The Hamilton Depression Scale(HAMD)was used to com-pare the improvement effect of depression status before and after intervention between two groups of patients.The Pittsburgh Sleep Quality Index(PSQI)was used to compare the changes in sleep quality before and after intervention between the two groups of pa-tients.The self-made Quality of Life Evaluation Scale was used to compare the changes in quality of life before and after interven-tion between the two groups of patients,and the clinical efficacy of the two groups of patients was also compared.Results:After in-tervention,the treatment effectiveness rate of the observation group was significantly better than that of the control group.The PSQI score and HAMD score of the observation group were significantly lower than those of the control group,and the quality of life score of the observation group was significantly higher than that of the control group.The differences between the two groups were statistically significant(Ps＜0.05).Conclusion:The combination of low-frequency repetitive transcranial magnetic stimulation and antidepressant drugs has a significant therapeutic effect on elderly chronic insomnia with depression,which can effectively al-leviate anxiety and depression,and improve sleep and quality of life.
关键词
重复经颅磁刺激/抗抑郁药物/老年慢性失眠症/抑郁/睡眠质量
Key words
Repetitive transcranial magnetic stimulation/Antidepressants/Elderly chronic insomnia/Depression/Sleep quality
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