世界睡眠医学杂志2024,Vol.11Issue(2) :454-457.DOI:10.3969/j.issn.2095-7130.2024.02.062

艾司西酞普兰联合运动方案对苯二氮(卓)类药物依赖焦虑症患者睡眠质量的影响

Effect of Escitalopram Combined Exercise Program on Sleep Quality of Patients with Benzodiazepine-dependent Anxiety Disorder

王惠强 王哲伟
世界睡眠医学杂志2024,Vol.11Issue(2) :454-457.DOI:10.3969/j.issn.2095-7130.2024.02.062

艾司西酞普兰联合运动方案对苯二氮(卓)类药物依赖焦虑症患者睡眠质量的影响

Effect of Escitalopram Combined Exercise Program on Sleep Quality of Patients with Benzodiazepine-dependent Anxiety Disorder

王惠强 1王哲伟1
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作者信息

  • 1. 泉州市第三医院科教科,泉州,362000
  • 折叠

摘要

目的:探讨艾司西酞普兰联合运动方案对苯二氮(卓)类(BDZ)药物依赖焦虑症患者睡眠质量的影响.方法:选取2021年9月至2023年2月泉州市第三医院收治的BDZ类药物依赖焦虑症患者120例作为研究对象,按照抛掷法随机分为对照组(n=58)和观察组(n=62).对照组仅予以艾司西酞普兰治疗,观察组予以艾司西酞普兰联合运动方案治疗.,比较2组睡眠质量、失眠程度、负性情绪以及生命质量.结果:治疗后,观察组匹兹堡睡眠质量指数(PSQI)中主观睡眠质量、入睡时间、睡眠效率、睡眠障碍、日间功能5个维度评分及总分均低于对照组,差异均有统计学意义(均P<0.05),失眠严重程度指数(ISI)评分低于对照组,差异有统计学意义(P<0.05);观察组汉密尔顿焦虑抑郁量表(HADS)评分均较对照组低,差异有统计学意义(P<0.05),健康调查简表(SF-36)评分较对照组高,差异有统计学意义(P<0.05).结论:艾司西酞普兰联合运动方案能明显提高BDZ类药物依赖焦虑症患者的睡眠质量,改善失眠症状,缓解负性情绪,提高生命质量.

Abstract

Objective:To investigate the effect of escitalopram combined exercise program on sleep quality of patients with benzo-diazepine(BDZ)-dependent anxiety disorder.Methods:A total of 120 patients with BDZ-dependent anxiety disorder who were ad-mitted to the hospital from September 2021 to February 2023 were selected,and randomly divided into the observation group(62 patients treated with escitalopram combined exercise program)and the control group(58 patients treated with escitalopram alone).Sleep quality,insomnia degree,negative emotions,and quality of life of the two groups were compared.Results:After treatment,the scores for subjective sleep quality,time to fall asleep,sleep efficiency,sleep disorder and daytime function in the Pittsburgh Sleep Quality Index(PSQI),and total score of the observation group were lower than those of the control group(Ps<0.05).The Insomnia Severity Index(ISI)score and Hospital Anxiety and Depression Scale(HADS)score were also lower than those of the conventional group(P<0.05).The MOS 36-item Short-form Health Survey(SF-36)score was higher than that of the convention-al group(P<0.05).Conclusion:Escitalopram combined with exercise program can significantly improve sleep quality,insomnia symptoms,negative emotions,and the quality of life of patients with benzodiazepine-dependent anxiety disorder.

关键词

艾司西酞普兰/运动方案/苯二氮(卓)类/药物依赖/睡眠质量

Key words

Escitalopram/Exercise Program/Benzodiazepine(BDZ)/Drug dependence/Sleep quality

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出版年

2024
世界睡眠医学杂志

世界睡眠医学杂志

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