Objective:To analyze the effects of examinations on sleep quality and fatigue after retroactive pre-control intervention of key failure points in magnetic resonance imaging(MRI)examination.Methods:A total of 84 experimental subjects were in-cluded in this study,all of whom were patients admitted to the hospital for MRI examination from June 2021 to June 2023,and were grouped according to the randomized numeric table method,and divided into the control group(routine care,a total of 42 ca-ses)and the experimental group(critical failure point traceability pre-control intervention,a total of 42 cases).Sleep quality,sleep parameters,fatigue,and psychological stress were compared between the two groups.Results:The test group was lower than the control group in terms of hypnotic medication,sleep disturbances,sleep efficiency and daytime dysfunction scores(P<0.05).The test group had lower sleep latency,lower number of awakenings,and longer total sleep time than the control group(P<0.05).In terms of Fatigue Severity Scale(FSS)score,Hamilton Anxiety Scale(HAMA)score and Hamilton Depression Scale(HAMD)score,the test group was lower than the control group(P<0.05).Conclusion:The key failure point traceability pre-control intervention is beneficial to improve sleep quality and sleep parameters,and reduce fatigue and psychological stress re-sponse in patients undergoing MRI examination,which can be further promoted and applied clinically.