Objective:To explore the effect of psychological combined sleep intervention on mental state and sleep quality of pa-tients with schizophrenia.Methods:A total of 83 patients with schizophrenia admitted to Fuzhou Neuropsychiatric Prevention and Treatment Hospital from February 2023 to September 2023 were randomly grouped by computer,consisting of a control group(n=41)and an observation group(n=42)by drawing a lot.The observation group received psychological combined sleep interven-tion;The psychological state evaluates and analyzes the sleep quality scores of each group of patients after simultaneous interven-tion.Results:After intervention,there was a significant difference in psychological state scores compared to before intervention,es-pecially in the observation group where anxiety and depression scores were significantly lower than those in the control group(P<0.05);in addition,in terms of sleep after intervention,the observation group's sleep score was significantly lower than that of the control group(P<0.05).Conclusion:Through the implementation of psychological combined sleep intervention for schizophrenia patients can effectively promote the adjustment of their mental state,improve the quality of sleep,extend the time to fall asleep,it is worth applying and promoting.