Objective:To study the depression,anxiety and sleep status of front-line medical staff one year after the end of the ep-idemic support mission of novel coronavirus in Wuhan,and explore the potential factors affecting sleep status.Methods:The Pitts-burgh Sleep Quality Index Quantity Table PSQI,the Widespread Anxiety Disorder Scale GAD-7,and Nine Patient Health Ques-tionnaires PQH-9 were conducted anonymously online on 130 frontline medical workers from the Gansu Province returning to Wu-han in March 2021.Results:1)The anxiety detection rate among frontline medical workers was 56.9%and depression was 63.1%.2)The total score of PSQI for medical staff is(8.28±3.74),with 73 people(56.2%)scoring above 7.The total score of doctor's sleep quality was(7.20±4.20)points,and the total score of nurse's sleep quality was(8.48±3.64)points.There was no statistically significant difference in sleep quality between doctors and nurses(P>0.05).3)There is a statistically significant difference in the total PSQI scores among medical staff of different ages(P<0.05).4)The degree of anxiety and depression of medical staff are positively related to the sleep quality.5)Depression is the main factor affecting the sleep quality of medical staff.Conclusion:After one year,some frontline medical staff in Wuhan had obvious anxiety,depression and sleep problems,especially young medical workers who had more prominent sleep problems,which indicated that it is necessary to pay attention to the contin-uous mental health of young medical workers after the aid to Hubei.