Objective:To investigate the clinical efficacy of inhalation of acetyl cysteine solution in the treatment of acute sinusitis and its influence on sleep quality.Methods:A total of 114 patients with acute sinusitis admitted to Chibi People's Hospital from April 2021 to April 2023 were chosen and separated into the control group(n=57,conventional drug)and the observation group(n=57,inhalation of acetyl cysteine solution based on the former group)according to the random number table method.The clin-ical efficacy,nasal sinus function,inflammatory factor levels and sleep quality were compared.Results:The observation group had higher total effective rate,the difference was statistically significant(P＜0.05).Symptom and visual analogue scale(VAS)scores in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).After treatment,SNOT-20,Lund-Kennedy scores and nasal airway resistance(NAR)in observation group were lower than those in control group,and the differences were statistically significant(P＜0.05).After treatment,the levels of TNF-α,CRP,IL-6,IL-8 and IL-l0,PSQI,and SRSS scores in the two groups significantly decreased,and the observation group were lower,and the differ-ences were statistically significant(P＜0.05).Conclusion:Atomization inhalation of acetyl cysteine solution in the treatment of a-cute sinusitis can significantly reduce nasal obstruction,purulent discharge and other symptoms,improve nasal cavity and sinus function,inhibit inflammatory response,achieve good therapeutic effect,and help patients recover good sleep quality,which is wor-thy of promotion.
关键词
急性鼻窦炎/乙酰半胱氨酸/临床疗效/炎症介质/睡眠质量
Key words
Acute sinusitis/Acetyl cysteine/Clinical efficacy/Inflammatory factors/Quality of sleep
维普
万方数据