Objective:To analyze the clinical efficacy of clindamycin gel and povidone-iodine solution in the treatment of bacteri-al vaginosis(BV)and their impact on patients'sleep quality.Methods:A total of 120 BV patients admitted to Qingkou Town Health Center in Minhou County,Fujian Province from January 2021 to June 2023 were selected as the research subjects.They were randomly divided into a control group and a treatment group,with 60 cases in each group,using a random number table method.The control group was treated with metronidazole orally,and the treatment group was treated with clindamycin phosphate vaginal gel combined with iodophor disinfectant on the basis of the control group.Compare the clinical efficacy,incidence of ad-verse reactions,and sleep quality between two groups of patients.Results:Patients in the observation group had a higher effective rate than the control group(P<0.05).There was no significant difference in the incidence of adverse effects between the two groups(P>0.05).The Pitsburg Sleep Quality Index Scale(PSQI)scores at treatment 3 d and 7 d was lower than the control group(P<0.05).Conclusion:The treatment of clindamycin gel and iodophor disinfectant can effectively improve the clinical treatment effect of BV patients,significantly improve their sleep quality,and have certain application value.