Objective:To analyze the impact of high-quality interventions on postoperative pain and sleep quality in patients un-dergoing gynecological surgery.Methods:A total of 98 gynecological surgery patients admitted to the Obstetrics and Gynecology Department of the First Affiliated Hospital of Xiamen University from January 2023 to January 2024 were selected as the research subjects.They were randomly divided into a control group and an observation group,with 49 cases in each group,using a random number table method.The control group received routine nursing intervention,while the observation group received high-quality nursing intervention.The Pittsburgh Sleep Quality Index(PSQI)was used to compare the differences in sleep quality between two groups of patients.The Self Rating Anxiety Scale(SAS)and Self Rating Depression Scale(SDS)were used to compare the im-provement of anxiety and depression symptoms between the two groups of patients.The Epworth Sleepiness Scale(ESS)was used to compare the changes in sleep quality before and after intervention between the two groups of patients.The differences in sleep effectiveness,sleep perception,and sleep sustainability between the two groups of patients were also compared.Multi channel Sleep Monitoring(PSG)was used to evaluate the sleep efficiency,rapid eye movement(REM)latency,sleep latency,wakefulness frequency,and post sleep wakefulness time of the two groups of patients.The tolerability of postoperative pain and nursing satisfac-tion were also compared between the two groups.Results:After intervention,the PSQI score,SAS score,SDS score,and ESS score of the observation group were significantly lower than those of the control group.The sleep efficiency and REM latency of the ob-servation group were higher than those of the control group.The sleep latency,number of awakenings,and wakefulness time after sleep of the observation group were significantly lower than those of the control group.The pain tolerance score of the observation group was significantly higher than that of the control group,and the nursing satisfaction of the observation group was significantly higher than that of the control group.The differences between the two groups were statistically significant(P<0.05).Conclu-sion:Implementing high-quality nursing interventions for gynecological surgery patients can not only alleviate postoperative pain,but also improve their sleep quality,accelerate the patient's recovery process,alleviate their anxiety and depression,and improve sleep efficiency.It is worth promoting and applying in clinical practice.