Objective:To analyze the effect of relaxation training combined with mindfulness decompression intervention on the sleep quality of postoperative thyroid surgery patients.Methods:A total of 100 thyroid cancer surgical patients admitted to the General Surgery Department of Xiamen University Affiliated First Hospital from January 2022 to December 2023 were selected as the study subjects.They were randomly divided into a control group and an observation group using a random number table meth-od,with 50 cases in each group.The Psychological Resilience Scale(CD-RISC)was used to evaluate the psychological resilience scores of two groups,the Sleep Disorder Scale(SDRS)was used to evaluate the occurrence of sleep disorders in two groups of pa-tients before and after intervention,and the Pittsburgh Sleep Quality Index(PSQI)was used to evaluate the sleep quality of the two groups of patients.Results:After intervention,the CD-RISC score of the psychological resilience scale in the observation group was significantly higher than that in the control group,while the SDRS score and PSQI score of the sleep disorders in the observa-tion group were significantly lower than those in the control group.The differences between the two groups were statistically signifi-cant(P<0.05).Conclusion:Relaxation training combined with mindfulness decompression intervention can enhance the psycho-logical resilience of postoperative thyroid surgery patients and improve their sleep quality,which is worthy of clinical promotion and application.