Objective:To evaluate the effect of non-invasive ventilation in the treatment of asthma-obstructive sleep apnea hypop-nea syndrome(OSAHS)overlap.Methods:A total of 72 patients with asthma-OSAHS overlap were enrolled,randomly divided in-to study group and control group,with 36 cases in each group.The control group received drug treatment,the study group received drug treatment+CPAP.The effect was evaluated at 12 th week.Respiratory and sleep parameters of polysomnography(PSG),ACT score and pulmonary function were compared.Results:After treatment,the apnea hypopnea index(AHI)of the study group was significantly lower than that of the control group,and the lowest blood oxygen saturation(LSpO2)and average blood oxygen satura-tion(ASpO2)were higher(P＜0.05).After treatment,the sleep latency(SL)of the study group was shorter than that of the con-trol group,and the sleep efficiency(SE)and N3％were higher than those of the control group,while N1％was lower.After treat-ment,the ACT score,peak expiratory flow(PEF),and FEV1/FVC％of the study group were higher than those of the control group(P＜0.05).Conclusion:Non invasive ventilation can improve the treatment effect of asthma combined with OSAHS to a certain extent.
关键词
哮喘/阻塞性睡眠呼吸暂停低通气综合征/无创通气/持续气道正压通气/多导睡眠图/肺功能
Key words
Asthma/Obstructive sleep apnea hypopnea syndrome/Non-invasive ventilation/Continuous positive airway pres-sure/Polysomnography/Pulmonary function
维普
万方数据