Objective:To observe the clinical effect of Gubenanshen Mixture on sleep disorder after chemotherapy in patients with colorectal cancer.Methods:From January 2021 to December 2023,60 patients with colorectal cancer complicated by chemothera-py and sleep disorders admitted to the outpatient department and inpatient department of Guangdong Second Middle School Hospi-tal were selected as the study objects,and were divided into control group and observation group according to random number table method,with 30 cases in each group.Pittsburgh Sleep Quality Index(PSQI)was used to compare the difference in sleep quality between the two groups.Self-rating Anxiety Scale(SAS)and KPS were used to evaluate the quality of life of cancer patients be-tween the two groups.Sleep duration,sleep efficiency and incidence of adverse reactions were compared between the two groups.Results:After intervention,PSQI score and SAS score of observation group were significantly lower than control group,KPS score of observation group was significantly higher than control group,sleep time and sleep efficiency of observation group were significantly higher than control group,and the incidence of adverse reactions of observation group was significantly lower than control group,the difference between the two groups was statistically significant(P＜0.05).Conclusion:Gubenanshen Mix-ture is safe and reliable for improving sleep disorder in patients with colorectal cancer after chemotherapy,and is worthy of clinical application.
关键词
固本安神合剂/结直肠癌/化疗/睡眠障碍/生命质量/疗效观察
Key words
Gubenanshen Mixture/Colorectal cancer/Chemotherapy/Sleep disorders/Quality of life/Curative effect observa-tion
维普
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