Objective:To elucidate the pathological mechanism and treatment direction of senile chronic bronchitis during acute attack,and to analyze the efficacy of ambroxol combined with antibiotics.Methods:A total of 70 patients with acute episodes of chronic bronchitis admitted to the Respiratory and Critical Care Medicine Department of Yangxin County Hospital of Traditional Chinese Medicine in Binzhou City,Shandong Province from March 2022 to July 2023 were selected as the research objects,and were divided into control group and observation group according to random number table method,with 35 cases in each group.The control group was given conventional treatment intervention,and the observation group was given ambroxol combined with antibiot-ics.The recovery of the two groups before and after intervention was compared,including dyspnea,cough,wet rales and length of hospital stay.The Pittsburgh sleep quality index was used to evaluate the changes in sleep quality of the two groups before and af-ter intervention,and the differences in lung function between the two groups were compared.The peak expiratory flow(PEF),forced expiratory volume in the first second(FEV1)and its ratio to forced vital capacity(FVC)(FEV1/FVC)were included,and the treatment effectiveness of the two groups was compared.Results:After treatment,the scores of dyspnea,cough,wet rales and other symptoms in the observation group were significantly lower than those in the control group,the PSQI scores in the observation group were significantly lower than those in the control group,the pulmonary function indexes in the observation group were signif-icantly higher than those in the control group,and the treatment effective rate in the observation group was significantly higher than that in the control group,the difference between the two groups was statistically significant(P＜0.05).Conclusion:Ambroxol combined with antibiotics can alleviate common symptoms,improve lung function and sleep in patients with chronic bronchitis,and improve treatment effectiveness,worthy of clinical application.
关键词
慢性支气管炎/老年人/急性发作期/氨溴索/抗生素/联合治疗/疗效/肺功能
Key words
Chronic bronchitis/the elderly/Acute attack stage/Ambroxol/Antibiotics/Combination therapy/Curative effect/Lung function
维普
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