Objective:To analysis the effect of psychological communication and sleep intervention on appeasing patients'anxiety and improving patients'sleep quality after surgery for liver cancer.Methods:A total of 60 patients recruited from January 2023 to December 2023 were divided into 2 groups by the random number table method.The control group(n=30)adopted basic nurs-ing;the observation group(n=30)used psychological communication and sleep intervention to compare the efficacy of clinical nursing.Results:The PSQI and HADS scores in the observation group were lower than those in the control group(P<0.05).Compared with the control group,the observation group demonstrated much higher SRAHP scores(P<0.05).Conclusion:The effect of psychological communication and sleep intervention for patients with liver cancer surgery is remarkable,which is helpful to improve the sleep quality of patients and relieve patients'hospital anxiety and depression,which is worth promotion and appli-cation.