世界睡眠医学杂志2024,Vol.11Issue(7) :1615-1617,1621.DOI:10.3969/j.issn.2095-7130.2024.07.057

COPD合并睡眠呼吸暂停综合征患者采用无创正压通气治疗的效果

Effects of Non-invasive Positive Pressure Ventilation Therapy in Patients with COPD and Sleep Apnea Syndrome

明安云 邓芳 肖祖国 鲁婷 段晓松 汪云亮
世界睡眠医学杂志2024,Vol.11Issue(7) :1615-1617,1621.DOI:10.3969/j.issn.2095-7130.2024.07.057

COPD合并睡眠呼吸暂停综合征患者采用无创正压通气治疗的效果

Effects of Non-invasive Positive Pressure Ventilation Therapy in Patients with COPD and Sleep Apnea Syndrome

明安云 1邓芳 1肖祖国 1鲁婷 1段晓松 1汪云亮1
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作者信息

  • 1. 竹溪县人民医院/十堰市太和医疗集团竹溪分院,竹溪,442300
  • 折叠

摘要

目的:探讨慢性阻塞性肺疾病(COPD)合并睡眠呼吸暂停综合征患者采用无创正压通气治疗的效果.方法:选取2021年1月至2023年1月竹溪县人民医院/十堰市太和医疗集团竹溪分院收治的COPD合并睡眠呼吸暂停综合征患者100例作为研究对象,按照随机数字表法分为对照组和观察组,每组50例.对照组接受常规治疗,观察组在此基础上实施无创正压通气(NIPPV)治疗.结果:观察组治疗后,动脉血pH值显著增加,差异有统计学意义(P<0.05),PaO2显著升高,差异有统计学意义(P<0.05),PaCO2显著降低,差异有统计学意义(P<0.05).与对照组比较,观察组在FVC、FEV1和FEV1/FVC%方面的改善均显著,差异有统计学意义(P<0.05).结论:在COPD合并睡眠呼吸暂停综合征患者中,NIPPV治疗能够有效改善动脉血气指标和肺功能指标.NIPPV通过提供正压通气支持,有助于改善患者的通气功能和呼吸机械性负荷.

Abstract

Objective:This study aimed to investigate the effects of non-invasive positive pressure ventilation(NIPPV)therapy in patients with COPD and sleep apnea syndrome.Methods:A total of 100 patients diagnosed with COPD and sleep apnea syn-drome,admitted to Zhuxi County People's Hospital/Shiyan Taihe Medical Group Zhuxi Branch from January 2021 to January 2023 were selected.They were randomly divided into an observation group(n=50)and a control group(n=50)according to random number table method.The control group received conventional treatment,while the intervention group received NIPPV therapy in addition to conventional treatment.Results:After intervention,the observation group exhibited significant increases in arterial blood pH,the difference was statistically significant(P<0.05),and significant increases in PaO2,the difference was statistically significant(P<0.05),and significant decrease in PaCO2,the difference was statistically significant(P<0.05).Compared to the control group,the observation group showed significant improvements in FVC,FEV1,and FEV1/FVC%,the difference was statis-tically significant(P<0.05).Conclusion:In patients with COPD and sleep apnea syndrome,NIPPV therapy effectively improved arterial blood gas indicators and lung function.NIPPV,by providing positive pressure ventilation support,is beneficial for enhan-cing ventilation function and reducing respiratory mechanical load in these patients.

关键词

COPD/睡眠呼吸暂停综合征/无创正压通气治疗

Key words

COPD/Sleep apnea syndrome/Non-invasive positive pressure ventilation therapy

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出版年

2024
世界睡眠医学杂志

世界睡眠医学杂志

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