世界睡眠医学杂志2024,Vol.11Issue(9) :1931-1933.DOI:10.3969/j.issn.2095-7130.2024.09.003

阿司匹林联合氯吡格雷治疗老年冠心病患者的疗效及对睡眠质量的影响

The Effect of Aspirin Combined with Clopidogrel on the Treatment of Elderly Patients with Coronary Heart Disease and Its Impact on Sleep Quality

薛华
世界睡眠医学杂志2024,Vol.11Issue(9) :1931-1933.DOI:10.3969/j.issn.2095-7130.2024.09.003

阿司匹林联合氯吡格雷治疗老年冠心病患者的疗效及对睡眠质量的影响

The Effect of Aspirin Combined with Clopidogrel on the Treatment of Elderly Patients with Coronary Heart Disease and Its Impact on Sleep Quality

薛华1
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作者信息

  • 1. 福建省福清市海口镇中心卫生院内科,福清,350313
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摘要

目的:探究阿司匹林联合氯吡格雷治疗老年冠心病患者的疗效及对睡眠质量的影响.方法:选取2023年1月至2023年6月福建省福清市海口镇中心卫生院内科收治的老年冠心病患者60例作为研究对象,按照随机数字表法分为对照组和观察组,每组30例.对照组采取氯吡格雷治疗,观察组在对照组治疗基础上加阿司匹林治疗.比较2组患者临床整体疗效、匹兹堡睡眠质量指数(PSQI)评分及心功能指标.结果:治疗后,观察组患者的疗效优于对照组(P<0.05);观察组患者PSQI的入睡时间、睡眠时间、睡眠效率、睡眠质量、睡眠障碍、催眠药物和日间功能障碍评分均低于对照组(P<0.05);观察组心功能指标左室射血分数(LVEF)高于对照组,且左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)相对较低(P<0.05).结论:阿司匹林联合氯吡格雷治疗老年冠心病患者可提升患者的疗效,提高患者睡眠质量,改善心功能,值得临床推广.

Abstract

Objective:To explore the therapeutic effect of aspirin combined with clopidogrel on elderly patients with coronary heart disease.Methods:Taking 60 elderly patients with coronary heart disease treated at Fuqing Haikou Town Central Health Center from January 2023 to June 2023 as the research object.Patients were randomly divided into a control group and an observa-tion group,with 30 patients in each group.The control group took clopidogrel,while the observation group added aspirin drug ther-apy on the basis of the former.The overall clinical efficacy,sleep quality and cardiac function indicators were compared between the two groups.Results:After treatment,the treatment effect of the control group was lower than that of the observation group(P<0.05).The sleep quality,sleep duration,sleep efficiency,sleep quality,sleep disorders,use of sleep medication,and daytime dys-function scores of the observation group patients were lower than those of the control group(P<0.05).Additionally,the left ven-tricular ejection fraction(LVEF)in the observation group was higher than that in the control group,and the left ventricular end-systolic diameter(LVESD)and left ventricular end-diastolic diameter(LVEDD)were relatively low(P<0.05).Conclusion:The combination of aspirin and clopidogrel for elderly patients with coronary heart disease improves the treatment efficacy,enhances sleep quality,and improves heart function.It is worth vigorously promoting and adopting in clinical practice.

关键词

阿司匹林/氯吡格雷/冠心病/睡眠质量

Key words

Aspirin/Elderly Coronary Heart Disease/Therapeutic Effects/Sleep Quality/Application Analysis

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出版年

2024
世界睡眠医学杂志

世界睡眠医学杂志

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