世界睡眠医学杂志2024,Vol.11Issue(9) :1948-1950.DOI:10.3969/j.issn.2095-7130.2024.09.008

氟派赛吨美利曲辛联合右佐匹克隆治疗睡眠障碍患者的效果研究

Effect of Fluoxetine-melitracen Combined with Eszopiclone in the Treatment of Patients with Sleep Disorders

李若霖
世界睡眠医学杂志2024,Vol.11Issue(9) :1948-1950.DOI:10.3969/j.issn.2095-7130.2024.09.008

氟派赛吨美利曲辛联合右佐匹克隆治疗睡眠障碍患者的效果研究

Effect of Fluoxetine-melitracen Combined with Eszopiclone in the Treatment of Patients with Sleep Disorders

李若霖1
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作者信息

  • 1. 福建省三明市将乐县总医院,三明,353300
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摘要

目的:探讨睡眠障碍治疗中选择氟派赛吨美利曲辛+右佐匹克隆的效果.方法:选取2022年1月至2024年2月福建省三明市将乐县总医院健康管理部收治的睡眠障碍患者60例作为研究对象,按照随机数字表法分为对照组和观察组,每组30例.对照组给予右佐匹克隆治疗,观察组在对照组基础上联合给予氟派赛吨美利曲辛治疗.采用匹兹堡睡眠质量指数(PSQI)量表评价2组护理前后睡眠质量变化情况,采用爱泼沃斯嗜睡量表(ESS)比较2组患者干预前后失眠改善情况,并比较2组患者的治疗疗效及不良反应发生率.结果:干预后,观察组PSQI评分、ESS评分显著低于对照组,观察组患者的治疗效果有效率显著高于对照组,观察组不良反应发生率显著低于对照组,差异均有统计学意义(均P<0.05).结论:氟派赛吨美利曲辛与右佐匹克隆联合使用,能够有效改善患者的睡眠质量,提高患者的治疗效率,降低不良反应发生率,值得临床推广应用.

Abstract

Objective:To investigate the effect of fluoxetine-melitracen combined with eszopiclone in the treatment of sleep disor-ders.Methods:A total of 60 patients with sleep disorders treated at the Health Management Department of the Jiangle County General Hospital from January 2022 to February 2024 were selected as research subjects.They were randomly divided into a con-trol group(n=30),which received eszopiclone treatment,and an observation group(n=30),which received fluoxetine-melitracen in addition to eszopiclone.The Pittsburgh Sleep Quality Index(PSQI)was used to evaluate changes in sleep quality before and af-ter treatment,and the Epworth Sleepiness Scale(ESS)was used to compare improvements in insomnia.The treatment efficacy and incidence of adverse reactions were also compared between the two groups.Results:After the intervention,the PSQI and ESS scores in the observation group were significantly lower than those in the control group.The treatment effectiveness in the observa-tion group was significantly higher,and the incidence of adverse reactions was significantly lower compared to the control group(P<0.05).Conclusion:The combination of fluoxetine-melitracen and eszopiclone is effective in improving sleep quality,in-creasing treatment efficiency,and reducing the incidence of adverse reactions in patients with sleep disorders.It is worthy of clini-cal promotion and application.

关键词

睡眠障碍/氟派赛吨美利曲辛/右佐匹克隆/不良反应/临床疗效/睡眠质量

Key words

Sleep disorders/Fluoxetine-melitracen/Eszopiclone/Adverse reactions/Clinical efficacy/Sleep quality

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出版年

2024
世界睡眠医学杂志

世界睡眠医学杂志

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