Effects of Dexmedetomidine Combined with Ischemic Preconditioning on Subjective Sleep Quality and Polysomnography in Patients with Cardiac Disease Undergoing Non-cardiac Surgery
Effects of Dexmedetomidine Combined with Ischemic Preconditioning on Subjective Sleep Quality and Polysomnography in Patients with Cardiac Disease Undergoing Non-cardiac Surgery
Objective:To analyze the sleep improvement effect of dexmedetomidine combined with ischemic preconditioning in patients with cardiac disease undergoing non-cardiac surgery.Methods:A total of 86 patients with cardiac disease undergoing non-cardiac surgery at First Affiliated Hospital of Xiamen University from February 2023 to February 2024 were selected for this study.The patients were randomly divided into a control group and an observation group,with 43 patients in each group based on their order of admission.All patients received combined intravenous and inhalation general anesthesia during surgery.The control group was given saline,while the observation group received dexmedetomidine combined with ischemic preconditioning.The inci-dence of postoperative cardiac and renal adverse events,polysomnography parameters,and subjective sleep quality were compared between the two groups.Results:The incidence of postoperative cardiac and renal adverse events was significantly lower in the ob-servation group compared to the control group(P＜0.05).After intervention,the total sleep time(TST)increased significantly,while sleep latency(SL),awake time(AT),and number of awakenings(NWAK)significantly decreased in both groups compared to pre-intervention levels(P＜0.05).Moreover,these improvements were more pronounced in the observation group compared to the control group(P＜0.05).Pittsburgh Sleep Quality Index(PSQI)scores significantly decreased in both groups after interven-tion(P＜0.05),with the observation group showing greater improvements compared to the control group(P＜0.05).Conclusion:Dexmedetomidine combined with ischemic preconditioning in patients with cardiac disease undergoing non-cardiac surgery reduces postoperative adverse events and helps improve sleep quality.
维普
万方数据