Gold plays an important role in various fields of modern society,and its reserves are scarce in nature,so the recovery of gold minerals is particularly important.The flotation test of a gold mine was carried out.When the grinding fineness was about-0.074mm80%,the dosage of Isoamyl xanthate was 90g/t,the dosage of butylammonium black was 25g/t,and the dosage of No.2 oil was 30g/t.under these conditions,the flotation test was carried out,and the gold concentrate with concentrate grade of 53.65g/t and gold recovery of 96.74%was obtained,and the gold grade of tailings was reduced to 0.13g/t.