首页|电针耳甲区对2型糖尿病大鼠胃肠动力的影响

电针耳甲区对2型糖尿病大鼠胃肠动力的影响

Impacts of electroacupuncture at auricular concha on gastrointestinal motility in the rats with type 2 diabetes

扫码查看
原文链接
  • NETL
  • NSTL
  • 维普
  • 万方数据
Objective:To observe the impacts of electroacupuncture(EA)at auricular concha on gastrointestinal motility in the rats with type 2 diabetes(T2D).Methods:A total of 30 SD male rats were collected.8 rats of them were in a control group and the rest 22 rats were prepared as the model of T2D by intraperitoneal injection with streptozotocin(STZ)and high-fat forage.Blood glucose≥16.7 mmol/L for 3 times was considered as modeling success in rats,thus the rats were collected in a T2D group(n=16).These 16 T2D rats were divided into a model group(n=8)and an intradermal auricular electroacupuncture stimulation(iaES)group(n=8)according to random number table.In the iaES group,intervention with EA was applied at auricular concha unilater-ally each time,once daily,on both sides alternatively,5-day treatment as 1 course,at the interval of 2 days between courses,totally for 4 weeks.No any intervention was given in the model group and the control group.At the end of 4 weeks of intervention,the gastric emptying and intestinal propulsion were determined,ELISA method was adopted to determine gastrin(GAS)and motilin(MTL),and random blood glucose value and food intake were recorded in the iaES group,the model group and the control group successively.Results:After modeling,as compared with the control group,the food intake and random blood glucose were increased significantly(both P＜0.001)and body weight was reduced obviously(P＜0.01)in the T2D group.After intervention for 4 weeks,compared with the model group,the food intake and gastric content weight were obviously reduced(both P＜0.05),the serum GAS content,gastric emptying and intestinal transit rate,as well as random blood glucose reduction were all higher(all P＜0.05)in the rats of the iaES group,but the difference was not significant in MTL between the iaES groups and the model group(P＞0.05).Conclusion:Electroacupuncture at auricular concha improves gastrointestinal motility in T2D model rats.

DiabetesType 2 diabetes mellitusVagus nerveGastrointestinal motilityAuricular conchaElectroacupuncture(EA)

杨森、吴雨蕊、詹铮、潘彦宏、姜劲峰

展开 >

南京中医药大学教育部针药结合重点实验室南京210023,中国

南京中医药大学教育部针药结合重点实验室210023,中国

Diabetes Type 2 diabetes mellitus Vagus nerve Gastrointestinal motility Auricular concha Electroacupuncture(EA)

Tradition Chinese Medicine Science Technology Project of Jiangsu ProvincePostgraduate Practice Innovation Program of Jiangsu Province

YB201808KYCX20_1544

2022

世界针灸杂志(英文版)
世界针灸学会联合会,中国中医研究院针灸研究所

世界针灸杂志(英文版)

CSTPCDCSCD
影响因子：0.375
ISSN：1003-5257
年,卷(期)：2022.32(2)
  • 2
  • 12