The subway station is the hub of the whole subway operation and plays an important role in improving the urban public transportation.The construction of subway station mainly includes surrounding enclosure engineering,foundation pit excavation,dewatering and supporting engineering,main structure construction and foundation pit backfilling engineering.The construction of the main structure is the most most crucial phase of the subway station project,and whether the construction scheme is reasonable or not directly affects the quality of the whole subway project.Taking the construction of Nanjing Metro Line 4 station as an example,this paper comprehensively expounds the construction scheme of the main structure of the station,and provides some reference for the construction of other such projects.