首页|近现代医家治疗病毒性脑炎组方用药规律分析

近现代医家治疗病毒性脑炎组方用药规律分析

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目的 通过数据挖掘分析近现代医家中医药治疗病毒性脑炎,总结近现代医家中医药治疗病毒性脑炎的用药规律.方法 检索古今医案云平台、中国知网、万方、维普中文期刊数据库(建库至2022年10月31日)和《名老中医经验全编》《中国名老中医药专家学术经验集》《中国近现代名中医医案精华》医案类书籍、收集有关病毒性脑炎的医案,提取中药处方.利用古今医案云平台和SPSS软件进行频次统计、关联分析、聚类分析,利用Cytoscape进行复杂网络分析,分析近现代医家治疗病毒性脑炎的高频药物、关键药对、常用方剂、核心处方.结果 共纳入148篇文献、167首方剂、260味中草药.高频中药为石菖蒲、甘草、大黄、金银花、郁金、连翘、钩藤、地黄、黄芩、石膏等22味,常用药物配伍包括石菖蒲-郁金、生地黄-玄参、石膏-知母等5对,常用方剂为清瘟败毒饮、小承气汤、菖蒲郁金汤等5种,常用中成药有安宫牛黄丸、紫雪丹等8种.结论 数据分析显示近现代医家治疗病毒性脑炎时攻补兼施,以清热解毒、化痰开窍、平肝息风、活血通络、行气通腑等治标的同时,还应重视益气、养阴等扶正药的使用.
Prescription Rules of Modern Doctors in Treatment of Viral Encephalitis
Objective To mine the data of modern doctors in the treatment of viral encephalitis with traditional Chinese medicine(TCM),and summarize their prescription rules.Methods The medical cases of viral encephalitis were collected by searching the Ancient and Modern Medical Records cloud platform,China National Knowledge Infrastructure(CNKI),Wanfang Data,and China Science and Technology Journal Database from the inception of the databases to Octo-ber 31,2022,as well as the medical case books such as The Complete Compilation of Experiences of Famous Old Chinese Medicine Practitioners(Ming Lao Zhong Yi Jing Yan Quan Bian),The Collection of Academic Experiences of Famous Old Chinese Medicine Experts in China(Zhong Guo Ming Lao Zhong Yi Yao Zhuan Jia Xue Shu Jing Yan Ji),and The Essence of Medical Cases of Famous Modern Chinese Medicine Practitioners in China(Zhong Guo Jin Xian Dai Ming Zhong Yi Yi An Jing Hua).The TCM prescriptions were extracted.Frequency statistics,correlation analysis and cluster analysis were performed using the Ancient and Modern Medical Records cloud platform and SPSS software,and complex network analysis was performed using Cytoscape to analyze the high-frequency medicines,key pairs,commonly used prescriptions and core prescriptions in the treatment of viral encephalitis.Results A total of 148 papers,167 prescriptions and 260 herbal medi-cines were included in this study.There were 22 high-frequency herbal medicines,including Acori Tatarinowii Rhizoma,Glycyrrhizae Radix Et Rhizoma,Rhei Radix Et Rhizoma,Flos Lonicerae Japonicae,Radix Curcumae,Fructus Forsythiae,Ramulus Uncariae Cum Uncis,Radix Rehmanniae,Radix Scutellariae,and Gypsum Filrosum.The commonly used herb pairs involved Acori Tatarinowii Rhizoma Radix Curcumae-Ramulus Uncariae Cum Uncis,raw Radix Rehmannia Radix Scrophulariae,Gypsum Filrosum-Rhizoma Anemarrhenae,and other two pairs.There were five commonly used prescrip-tions,including Qingwen Baidu Decoction,Small Chengqi Decoction,Changpu Yujin Decoction,and eight commonly used Chinese patent medicines,including Angong Niuhuang Pill and Zixue Pill.Conclusion The data reveals that modern doc-tors treat viral encephalitis with both tonification and elimination,treating the symptoms by clearing heat,removing toxin,resolving phlegm,opening orifices,soothing liver,extinguishing wind,activating blood,dredging collaterals,moving qi and unblocking fu-organs.They also pay attention to the use of medicines for reinforcing healthy qi such as those for replenis-hing qi and nourishing yin.

Viral encephalitisToxinAcori Tatarinowii RhizomaPrescription ruleTraditional Chinese medicine

李兰、孙文军、郑琴

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北京中医药大学第三附属医院,北京 100029

病毒性脑炎 石菖蒲 用药规律 中医药

北京市科技计划课题首都特色项目

Z171100001017227

2024

世界中西医结合杂志
中华中医药学会

世界中西医结合杂志

CSTPCD
影响因子:1.053
ISSN:1673-6613
年,卷(期):2024.19(1)
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