Prescription Rule of Gong Tingxian of Ming Dynasty in the Treatment of Dermatitis and Eczema Diseases
Objective To analyze the prescription data in the treatment of dermatitis and eczema diseases by Gong Tingxian of Ming Dynasty,to provide reference for clinical treatment of the diseases.Methods Literature involving the application of Gong's prescriptions for the treatment of dermatitis and eczema diseases was collected from Gong Tingx-ian's Complete Medical Book(Gong Ting Xian Yi Xue Quan Shu)to establish a database of the prescriptions.The frequen-cy of usage,source,toxicity,nature,flavor,channel tropism,and efficacy of the medicinal herbs were analyzed by SPSS Sta-tistics 22.0.Association rules of high-frequency herbs were mined by SPSS Modeler 18.0,and Origin2022b was used for hierarchical cluster analysis of high-frequency herbs and data visualization.Results A total of 110 prescriptions were collected,including 29 ones for internal use and involving 76 Chinese medicinal herbs with a total frequency of 309.Radix Et Rhizoma Glycyrrhizae,Herba Schizonepetae,Rhizoma Chuanxiong,Radix Angelicae Sinensis,Radix Saposhnikovia,Fructus Forsythiae,Radix Scutellariae,Radix Sophorae Flavescentis,and Rhizoma Cptidis were most frequently used.The main efficacy was to clear heat and resolve the exterior.The core combination obtained through association analysis was Herba Schizonepetae-Rhizoma Chuanxiong-Radix Et Rhizoma Glycyrrhizae-Fructus Forsythiae.Five herb groups were obtained through cluster analysis.There were 81 prescriptions for external use,involving 118 Chinese medicinal herbs with a total frequency of 360.Alum,mercury,sulfur,arsenic,realgar,maple,pricklyash peel and red lead were most frequently used,with the efficacy of counteracting toxic substance,killing worms,relieving itching,drawing out toxin,suppuration and promoting granulation.The core combination was alum-mercury.Four herb groups were obtained through cluster analysis.Whether for internal use or external use,the medicinal herbs had equal proportion in cold and warm property,and they were mainly bitter,pungent and sweet,predominantly acting on lung,stomach,spleen and liver.Conclusion In Gong's differen-tiation and treatment of dermatitis and eczema diseases,the main causes of wind and heat were emphasized.For internal therapy,Gong pays attention to regulating qi movement,while for external therapy,he focuses on reducing toxin and enhan-cing efficacy.In addition,Gong takes into account the medication time and method,with regulation and prevention empha-sized.Internal and external therapies are combined,and both efficacy and safety are considered,which deserves further study and reference.
Gong TingxianDermatitis and eczema diseasesData miningPrescription rule
万方数据
维普
