Clinical Observation on Huangqi Zhuye Decoction Combined with Yiqi Shengjin Pill in Treating Type 2 Diabetes Mellitus with Deficiency of Qi and Yin
Objective To observe the clinical effect of Huangqi Zhuye Decoction combined with Yiqi Shengjin Pill in treating type 2 diabetes mellitus with deficiency of Qi and Yin.Methods Ninety patients with type 2 diabetes mel-litus(T2DM)treated in Anyang Hospital of TCM in Henan from January 2020 to January 2022 were selected as the re-search objects,and divided into a control group and a treatment group according to random number table,45 cases in each one.The grouping method was.The conventional Western medicine was used in the two groups.Huangqi Zhuye Decoction was used in the control group,and Yiqi Shengjin Pill was applied in the treatment group on the basis of the control group.All the interventions were continuously for three months.The clinical effect,the incidence of adverse reactions were ob-served;the Traditional Chinese Medicine(TCM)syndrome score,the blood glucose indices[fasting plasma glucose(FPG),glycosylated hemoglobin(HbA1c),fasting insulin(FINS)]and serum inflammatory factors[C-reactive protein(CRP),in-terleukin-1,(IL-1β),interleukin-6(IL-6)]before and after treatment were compared.Results After treatment,the total effective rate in the treatment group was 91.11％(41/45),which was significantly higher than 75.55％(34/45)in the control group,with statistical significance(P＜0.05).After treatment,the scores of TCM syndromes in both the two groups were lower than those before treatment,and the difference was statistically significant(P 0.05);the scores of the main symptoms and the secondary symptoms in the treatment group were lower than those in the control group,and the difference was statistically significant(P＜0.05).After treatment,the blood glucose indices FPG,FINS and HbA1c in the two groups were lower than those before treatment,and the difference was statistically significant(P＜0.05).The FPG,FINS and HbA1c in the treatment group were lower than those in the control group,with statistical significance(P＜0.05).After treatment,the levels of serum inflammatory factors CRP,IL-6 and IL-1β in the two groups were lower than those before treatment,and the difference was statistically significant(P＜0.05);CRP,IL-6 and IL-1β in the treatment group were lower than those in the control group,with statistical significance(P＜0.05).The incidence of adverse reac-tions between the two groups during the treatment showed no significant difference(P＞0.05).Conclusion Huangqi Zhuye Decoction combined with Yiqi Shengjin Pill are an effective and safe scheme for the treatment of type 2 diabetes Mellitus,which can obviously control the blood glucose of the patients and reduce the inflammatory reaction.
Huangqi Zhuye DecoctionYiqi Shengjin PillsType 2 Diabetes MellitusDeficiency of Yin and Qi
万方数据
维普
