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慢性阻塞性肺疾病急性加重期中医证型结构方程分析

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目的 为慢性阻塞性肺疾病急性加重期(Acute Exacerbation of Chronic Obstructive Pulmonary Dis-ease,AECOPD)临床辨证诊断和证型的量化标准提供参考依据.方法 通过临床调研,应用先进的数理统计方法结构方程对AECOPD中医证候进行系统的研究.收集病例资料100例,数据分析软件选择R语言,首先经过探索性分析,利用最大方差旋转方法,提取出五个共因子,归纳为F1至F5,依据中医理论进行证型辨证命名.结果 通过结构方程初步揭示了 AECOPD的疾病的五个常见的证型:风寒证、肾虚证、脾虚证、阴虚证、痰湿证,同时分析出了五大常见证型的辨证要点.AECOPD结构方程中各因子与临床证型间存在着较好的对应关系.结论 AECOPD的基础证型是风寒、肾虚、脾虚、阴虚、痰湿证等.
Structural Equation of TCM Syndromes in Acute Exacerbation of Chronic Obstruc-tive Pulmonary Disease
Objective To provide reference for clinical syndrome differentiation and establishing the quantitative standard of TCM syndromes in acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods After clinical investigation,structural equation,an advanced statistical method,was employed to systematically study the TCM syndromes of AECOPD.The data of 100 cases were collected and analyzed by the R language.After exploratory analysis,five common factors(Fl-F5)were extracted by the maximum variance rotation method,and then the syndromes were dif-ferentiated and named according to the TCM theory.Results The structural equation revealed five common TCM syn-dromes of AECOPD,which were wind-cold,kidney deficiency,spleen deficiency,yin deficiency,and phlegm-dampness,and the key points for syndrome differentiation were summarized.There was a good corresponding relationship between the factors in the structural equation and the TCM syndromes of AECOPD.Conclusion Wind-cold,kidney deficiency,spleen deficiency,yin deficiency,and phlegm-dampness were the common TCM syndromes of AECOPD.

Acute Exacerbation of Chronic Obstructive Pulmonary Disease(AECOPD)TCM SyndromeStructural EquationMathematical Statistics

丁敏、王冰、贾春红

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江苏省泰州市中医院重症医学科,江苏泰州 225300

慢性阻塞性肺疾病急性加重期 中医证候结构方程 数理统计

泰州市科技支撑社会发展计划(指导性)项目(2017)

2024

世界中西医结合杂志
中华中医药学会

世界中西医结合杂志

CSTPCD
影响因子:1.053
ISSN:1673-6613
年,卷(期):2024.19(3)
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