Visualizing and Exploring Research Hotspots and Frontiers of Traditional Chinese Medicine in the Treatment of Colorectal Cancer with Citespace
Objective To examine and condense the research on traditional Chinese medicine for treating colorec-tal cancer with the help of scientific knowledge graph software.Methods The relevant literature from 2002 to 2022 in this field was searched by China National Knowledge Infrastructure(CNKI).The authors'information,research institutions,and main contents of these articles were analyzed scientifically and accurately by using CiteSpace software.Results A total of 731 articles were included.Leading core author teams such asYang Yufei,Jiang Yilan,and Jin Heiying,and main institu-tions including Xiyuan Hospital,China Academy of Chinese Medical Sciences,Jiangsu Provincial Hospital of Traditional Chinese Medicine,Hunan Provincial Hospital of Integrated Traditional Chinese and Western Medicine are involved to carry out related research.High-frequency keywords include chemotherapy,apoptosis,oxaliplatin,proliferation,intestinal flora,and immune function.The mechanism of action,tumor metastasis,and pharmacology are the hot spots and frontiers of tradi-tional Chinese medicine in the treatment of colorectal cancer in recent 20 years.Conclusion The analysis of the knowl-edge graph can help to summarize the focus of domestic research on the treatment of colorectal cancer with traditional Chi-nese medicine.Key questions and recent progress over the past 20 years are explored to grasp the direction for future re-search on the relationship between traditional Chinese medicine and colorectal cancer.
Traditional Chinese Medicine TreatmentColorectal CancerCiteSpaceKnowledge Graph