Clinical Efficacy of Hongteng Baijiang Erdan Decoction Combined with Microwave Therapy in the Treatment of Sequela of Pelvic Inflammatory Disease with Dampness-Heat and Stasis Accumulation
Objective To evaluate the clinical efficacy of Hongteng Baijiang Erdan Decoction combined with mi-crowave therapy for treating the sequelae of pelvic inflammatory disease(SPID)characterized by dampness-heat and stasis accumulation.Methods A total of 98 SPID patients with dampness-heat and stasis accumulation admitted to the gyneco-logical inpatient and outpatient clinics of Qian'an City Hospital of Traditional Chinese Medicine from January 2020 to March 2023 were selected.They were divided into a control group and a treatment group by random number table,with 49 in each group.The control group received azithromycin tablets,while the treatment group received oral administration of Hongteng Baijiang Erdan Decoction combined with microwave therapy.Both groups were treated continuously for 14 days as one course of treatment.The total effective rate and recurrence rate at a three-month follow-up were observed and com-pared alongside serum inflammatory markers[(interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),C-reactive protein(CRP)],hemorheological parameters(high-shear whole blood viscosity,low-shear whole blood viscosity,plasma viscosity),and TCM syndrome(dampness-heat and stasis accumulation)scores before and after treatment.Results The total effective rate of the treatment group was 95.83％(46/48),higher than the 80.85％(38/47)of the control group,and the recurrence rate of the treatment group at 4.17％(2/48)was lower than the control group at 17.02％(8/47)(P＜0.05).After treatment,both groups demonstrated reductions in serum CRP,IL-6,and TNF-α compared with the condi-tions before treatment,with the treatment group showing lower levels than the control group(P＜0.05).Similarly,all hemo-rheological indices measured were decreased after treatment in both groups(P＜0.05),with the treatment group having greater reductions(P＜0.05).Symptom scores related to abnormal vaginal discharge,menstrual disturbances,lumbosacral pain,lower abdominal stabbing or distension,yellowish-red urine,and dry stool were all reduced following treatment(P＜0.05),with the treatment group demonstrating a more significant decrease than the control group(P＜0.05).Conclu-sion Hongteng Baijiang Erdan Decoction combined with microwave therapy is more effective than azithromycin alone in treating the sequelae of SPID characterized by dampness-heat and stasis accumulation,and can reduce the recurrence rate.
Sequela of pelvic inflammatory diseaseHongteng Baijiang Erdan DecoctionMicrowave therapyDampness-heat and stasis accumulation
万方数据
维普
