首页|基于聚类分析的杨晋翔教授治疗萎缩性胃炎的用药规律及学术思想

基于聚类分析的杨晋翔教授治疗萎缩性胃炎的用药规律及学术思想

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目的 探究杨晋翔教授辨证治疗萎缩性胃炎(Chronic atrophic gastritis,CAG)的遣方用药规律和主要学术思想.方法 收集2019年1月-2019年12月期间杨晋翔教授门诊确诊的CAG患者病历资料及首诊中药处方,共262例,运用IBM SPSS Statistics 25统计学软件对录入的数据进行频数分析,运用IBM SPSS Modeler 18统计学软件进行聚类分析.结果 通过对262例患者的首诊中药处方进行频数分析,总结出杨晋翔教授在辨证治疗CAG时应用频率最高的两味药物为徐长卿和青蒿;使用IBM SPSS Statistics 25统计学软件对出现频次≥40次的药物进行聚类分析,得出杨晋翔教授治疗CAG的六个核心中药处方.结论 杨晋翔教授治疗CAG时擅用温性及寒性药物,擅用苦、辛、甘味药物;药物多归于肝、胃、脾三经;重视畅达肝气;健脾以和胃,脾胃同治;以"平"为度论治中焦;辨证与辨症相结合,标本兼治;同时注重化瘀解毒;临床疗效满意.
Medication Rules and Academic Thoughts of Professor Yang Jinxiang in the Treat-ment of Chronic Atrophic Gastritis Based on Cluster Analysis
Objective To explore Professor Yang Jinxiang's medication rules and main academic thoughts in the syndrome differentiation and treatment of chronic atrophic gastritis(CAG).Methods Medical records and first-visit Chinese medicine prescriptions of 262 CAG patients diagnosed by Professor Yang from January 2019 to December 2019 were collected.The data were analyzed using IBM SPSS Statistics 25 for frequency analysis and IBM SPSS Modeler 18 for cluster analysis.Results Frequency analysis of the first-visit Chinese medicine prescriptions of 262 patients revealed that the two most frequently used drugs by Professor Yang in the treatment of CAG based on syndrome differentiation were Cynanchi Paniculati Radix et Rhizoma and Artemisiae Annuae Herba.Cluster analysis using IBM SPSS Statistics 25 on drugs with a frequency of≥40 times identified six core Chinese medicine prescriptions for treating CAG.Conclusion Professor Yang is skilled in using both warm and cold drugs,and prefers those with bitter,pungent,and sweet flavors.The drugs predominantly target the liver,stomach,and spleen meridians.Professor Yang emphasizes the importance of soothing liver qi,harmonizing the stomach by strengthening the spleen,and treating both the spleen and stomach concurrently.More-over,he advocates for a balanced approach to treating the middle energizer and combines syndrome differentiation with symptom differentiation for both root and manifestation treatment.Additionally,he focuses on resolving stasis and removing toxin,with satisfactory clinical outcomes achieved.

Yang JinxiangAtrophic GastritisCluster AnalysisData MiningTraditional Chinese MedicineMedi-cation Rules

杨英姿、杨晋翔、陈泽慧、王瑞瑞、安静

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北京市门头沟区中医医院脾胃病科,北京 102300

北京中医药大学第三附属医院,北京 100029

中国中医科学院中医药信息研究所科教处,北京 100091

北京市丰台区中医医院(南苑医院)脑病科,北京 100071

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杨晋翔 萎缩性胃炎 聚类分析 数据挖掘 中医 用药规律

国家自然科学基金面上项目首都卫生发展科研专项重点攻关项目北京中医药薪火传承"3+3"工程基层老中医传承工作室建设项目

81173232首发2018-4-4072

2024

世界中西医结合杂志
中华中医药学会

世界中西医结合杂志

CSTPCD
影响因子:1.053
ISSN:1673-6613
年,卷(期):2024.19(6)