Mining of TCM Master Lu Zhizheng's Medication Rules in the Treatment of Epigas-tric Pain Due to Dampness-Heat Obstructing Middle Energizer Based on Associa-tion Rules Analysis
Objective To analyze the clinical symptoms,medication characteristics,compatibility rules,and drug-symptom relationship of the TCM master Lu Zhizheng in treating epigastric pain due to dampness-heat obstructing mid-dle energizer by data mining from medical records.Methods The medical records of the patients with epigastric pain due to dampness-heat obstructing middle energizer treated by Professor Lu Zhizheng in the outpatient department of Guang'anmen Hospital and Sanzhitang Clinic were collected.Epidata 3.1 was used to build a medical case library.The Apriori al-gorithm in SPSS Modeler 14.2 was used for association rules analysis.Results(1)A total of 258 medical records were included,involving 6 syndromes,10 therapies,258 prescriptions,and 163 medicines with the total frequency of 2 955.There were 20 medicines with the frequency above 15.(2)With the thresholds of support≥ 15％and confidence≥ 100％,3 sec-ond-order association rules and 13 third-order medicine-medicine association rules were mined out.With the thresh-olds of support≥10％and confidence≥ 100％,9 second-order association rules,23 third-order association rules,and 12 fourth-order symptom-medicine association rules were mined out.Conclusion The association rules reveal Professor Lu Zhizheng's academic thought and medication characteristics of ventilating the upper energizer,dredging the middle ener-gizer,and moistening the lower energizer in treating epigastric pain due to dampness-heat obstructing middle energizer.The findings provide a scientific basis and data reference for further research on Professor Lu Zhizheng's academic thought and medication experience.
Lu ZhizhengEpigastric PainData MiningAssociation Rules
万方数据
维普
