世界中西医结合杂志2024,Vol.19Issue(8) :1541-1545,1570.DOI:10.13935/j.cnki.sjzx.240810

倪青教授诊治糖尿病的临证经验及用药规律研究

Clinical Experience and Medication Regularity of Professor NI Qing against Diabetes

刘婕 姜敏 倪青 冯兴中
世界中西医结合杂志2024,Vol.19Issue(8) :1541-1545,1570.DOI:10.13935/j.cnki.sjzx.240810

倪青教授诊治糖尿病的临证经验及用药规律研究

Clinical Experience and Medication Regularity of Professor NI Qing against Diabetes

刘婕 1姜敏 1倪青 2冯兴中3
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作者信息

  • 1. 首都医科大学附属北京世纪坛医院中医科,北京 100038
  • 2. 中国中医科学院广安门医院,北京 100053
  • 3. 清华大学玉泉医院,北京 100040
  • 折叠

摘要

目的 通过数据挖掘研究倪青教授治疗糖尿病(Diabetes mellitus,DM)的用药规律及核心处方,探讨倪青教授诊治DM早期的临证经验及学术思想.方法 通过临床医案采集,结合软件的分析系统,采用频次统计法,统计得出治法出现频次及中药性味归经频次;采用关联规则分析法,统计得出处方中药物组合使用频次及药物之间的关联规则,采用Cytoscape3.7.1进行可视化展示.结果 通过对99例DM早期患者进行分析,高频药物有茯苓,泽泻,甘草,猪苓,佩兰,藿香等;药物组合有"猪苓,茯苓""猪苓,泽泻""藿香,佩兰""厚朴,半夏""炒白术,茯苓""车前子,川牛膝""太子参,茯苓""冬瓜仁,冬瓜皮""泽兰,泽泻""生黄芪,太子参""檀香,丹参,砂仁"等.结论 倪青教授辨证治疗DM早期重视病证结合,从湿、虚、瘀、浊着手,治以健脾祛湿,疏瘀化浊.

Abstract

Objective To investigate the medication regularity and core prescription of professor NI Qing against diabetes by data mining in order to provide references for the clinical treatment of diabetes mellitus(DM).Methods By collecting clinical medical records and combining them with the analysis system of the software,the frequency statistics method was used to calculate the occurrence frequency of treatment methods and the frequency of properties and flavors of traditional Chinese medicine(TCM)acting on different channels.Association rule analysis was used to statistically deter-mine the frequency of TCM drug combinations used in the prescriptions and the association rules between drugs.Cytoscape 3.7.1 was adopted for visual display.Results A total of 99 cases of patients with early DM were analyzed.Drugs with high frequency include Poria,Rhizoma Alismatis,Radix et Rhizoma Glycyrrhizae,Polyporus Umbellatus,Eupatorii Herba,and Herba Pogostemonis.The drug combinations include"Polyporus Umbellatus+Poria","Polyporus Umbellatus+Rhizo-ma Alismatis","Herba Pogostemonis+Eupatorii Herba","Cortex Magnoliae Officinalis+Rhizoma Pinelliae","fried Rhi-zoma Atractylodis Macrocephalae+Poria","Semen Plantaginis+Cyathulae Radix","Radix Pseudostellariae+Poria","Semen Benincasae+Exocarpium Benincasae","Eupatorium japonicum+Rhizoma Alismatis","raw Radix Astragali+Radix Pseudostellariae",and"Lignum Santalialbi+Radix et Rhizoma Salviae Miltiorrhizae+Fructus Amomi".Conclusion Professor NI Qing attaches great importance to the symptoms in the diagnosis and treatment of early DM,starting with dampness,deficiency,blood stasis,and turbidity to treat the disease by strengthening the spleen,removing dampness,and removing blood stasis and turbidity.

关键词

倪青/2型糖尿病/数据挖掘/学术经验传承/用药规律

Key words

NI Qing/Type 2 Diabetes Mellitus/Data Mining/Academic Experience Inheritage/Medication Regu-larity

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基金项目

中医药循证能力建设项目(2019XZZX-JB004)

国家中医药管理局、国家卫生计生委办公厅、中央军委后勤保障部卫生局重大疑难疾病中西医临床协作试点项目(国中医药医政发[2018]3号)

首都卫生发展科研专项项目(2016-1-4151)

出版年

2024
世界中西医结合杂志
中华中医药学会

世界中西医结合杂志

CSTPCD
影响因子:1.053
ISSN:1673-6613
参考文献量17
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