首页|基于气血水理论探析肠道菌群与代谢相关脂肪性肝病的相关性

基于气血水理论探析肠道菌群与代谢相关脂肪性肝病的相关性

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代谢相关脂肪性肝病(Metabolic associated fatty liver disease,MAFLD)为一种慢性肝病,中医气血水理论是从气、血、水角度阐述人体病理生理变化,论述人体疾病的发生、发展过程.文中从人体精微物质"气、血、水"角度探析气血水、肠道菌群及代谢相关脂肪性肝病三者之间的关系,并从气血水调和、肝脾功能正常及肠道菌群动态平衡层次阐明,肠道菌群代谢产物、肠道黏膜屏障等改变可促进代谢相关脂肪性肝病相关的病理改变,从而影响代谢相关脂肪性肝病的病程进展,主张调节肝脾功能来调控肠道菌群,以此来达到治疗代谢相关脂肪性肝病的目的.
Correlation between Intestinal Flora and Metabolic-Associated Fatty Liver Disease Based on the Theory of Qi-Blood-Water
Metabolic-associated fatty liver disease(MAFLD)is a chronic liver disease.The theory of qi-blood-water in traditional Chinese medicine describes the pathophysiological changes of the human body and the occurrence and development of human diseases from the perspectives of qi,blood,and water.According to this theory,this paper ex-plores the relationship among qi-blood-water,intestinal flora,and MAFLD.From the harmony of qi,blood,and water,the normal functions of liver and spleen,and the dynamic balance of intestinal flora,this paper clarifies that the changes of in-testinal flora metabolites and intestinal mucosal barrier can promote the pathological changes,thus affecting the progression of MAFLD.It is suggested that the functions of liver and spleen can be regulated to recover the intestinal flora in the treat-ment of MAFLD.

Metabolic Associated Fatty Liver DiseaseIntestinal FloraFunctions of Liver and SpleenQi-Blood-Water

赵美怡、王少丽、吕文良

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北京中医药大学研究生学院,北京 100020

中国中医科学院广安门医院,北京 100032

代谢相关脂肪性肝病 肠道菌群 肝脾功能 气血水

国家重点研发计划中医药现代化研究重点专项国家自然科学基金面上项目中国中医科学院科技创新工程中国中医科学院科技创新工程

2018YFC170570281774282CI2021A00801CI2021A00804

2024

世界中西医结合杂志
中华中医药学会

世界中西医结合杂志

CSTPCD
影响因子:1.053
ISSN:1673-6613
年,卷(期):2024.19(8)
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