Objective To explore and analyze the prescription patterns of Professor Sun Liyun in treating lichen planus(LP)with wind-dampness accumulation in the skin syndrome through the Traditional Chinese Medicine Inheritance Support Platform.Methods Medical records of Professor Sun Liyun's outpatient treatment of LP with wind-dampness ac-cumulation in the skin syndrome from February 2019 to October 2023 were collected and organized,followed by standard-ized input.The data were then analyzed using association rule analysis and complex system entropy clustering analysis.Re-sults A total of 71 LP patients with wind-dampness accumulation in the skin syndrome were included,with a male-to-female ratio of 1∶1.3 and a mean age of(49.65±16.60)years.(1)A total of 32 drugs were used with a frequency of≥30,including Uncariae Ramulus cum Uncis,Spatholobi Caulis,and Cynanchi Paniculati Radix et Rhizoma.(2)The drugs were mostly cold in nature and bitter in flavor,primarily acting on the liver and stomach meridians.(3)Complex system en-tropy clustering analysis identified 19 high-frequency drug pairs,including combinations such as Spatholobi Caulis-Un-cariae Ramulus cum Uncis,26 core drug combinations such as Citri Fructus-Sappan Lignum-Sparganii Rhizoma,and 13 new prescriptions including Citri Fructus-Sappan Lignum-Sparganii Rhizoma-Liquidambaris Fructus-Acori Tatari-nowii Rhizoma.Conclusion Professor Sun Liyun believes that the main pathogenesis of LP with wind-dampness accu-mulation in the skin is rooted in yin-yang imbalance,with wind,dampness,heat,stasis,and toxins as manifestations.The treatment focuses on regulating yin and yang,dispelling wind and dampness,clearing heat,and activating blood circulation,while also considering the nourishment of the spleen and stomach and regulating emotions.This approach provides a refer-ence for the clinical prescription of LP and the development of new medications.
关键词
扁平苔癣/中医传承辅助平台/数据挖掘/用药经验分析
Key words
Lichen Planus/Traditional Chinese Medicine Inheritance Support System/Data Mining/Analysis of Medication Experience
维普
万方数据