Clinical Efficacy of Modified Sangjuyin Combined with Anti-Infection Treatment and Its Effect on TCM Syndrome Score and T Lymphoid Subsets in Children with Wind-Heat-Induced Pulmonary Pneumonia
Objective To explore the clinical efficacy of modified Sangjuyin combined with anti-infection treat-ment and its effect on TCM syndrome scores and T lymphoid subsets in children with wind-heat-induced pulmonary pneumonia.Methods A total of 90 children with pneumonia admitted to Tongling Hospital of Traditional Chinese Medi-cine from August 2022 to August 2023 were selected and divided into control group and study group by simple random number table method,with 45 cases in each group.On the basis of conventional symptomatic treatment,the control group was treated with anti-infection treatment,and the study group was treated with modified Sangjuyin on the basis of the con-trol group for seven days.The clinical efficacy,occurrence of adverse reactions,TCM syndrome scores,T lymphoid subsets(CD3+,CD4+,and CD4+/CD8+)levels,and inflammatory indicators[procalcitonin(PCT),white blood cell count(WBC),and C-reactive protein(CRP)]levels of the two groups were analyzed before and after treatment.Results After treatment,the total clinical effective rate of the study group was 93.33%(42/45),which was significantly higher than that of the control group 77.78%(35/45),and the difference was statistically significant(P<0.05).The scores of sore throat,yellow and thick phlegm,ungratifying coughing,fever and anorexia,thirst,gasping,nasal congestion,and runny nose in the two groups were lower than before treatment(P<0.05),and the TCM syndrome score of the study group was significantly lower than that of the control group(P<0.05).After treatment,the levels of CD3+,CD4+,and CD4+/CD8+in the two groups were higher(P<0.05),and the T lymphoid subgroup index of the study group was significantly higher than that of the control group(P<0.05).After treatment,the levels of serum PCT,WBC,and CRP in the two groups were lower(P<0.05),and the inflammation index of the study group was significantly lower than that of the control group(P<0.05).During the treatment period,the incidence of adverse reactions in the study group was 6.67%(3/45)compared with 4.44%(2/45)in the control group,and the difference was not statistically significant(P>0.05).Conclusion Conven-tional anti-infection combined with modified Sangjuyin for wind-heat-induced pulmonary pneumonia can effectively re-lieve the clinical symptoms of children,regulate the immune function,reduce the degree of inflammation,and improve the overall treatment effect of disease,and it is safe.