Data Mining of Medication Rules of TCM Master HE Ren in the Syndrome Differen-tiation and Treatment of Gastrointestinal Cancer
Objective To study the medication characteristics and compatibility rules of Professor He Ren,a TCM master,in the syndrome differentiation and treatment of gastrointestinal cancer patients by data mining of medical records.Methods The medical records of 822 gastrointestinal cancer patients treated by Professor He Ren from June 2008 to Oc-tober 2011 were collected to build a medical case library.Then,the medicine frequency,doses of main medicines,and com-patibility rules were analyzed,and the hierarchical cluster analysis was performed.Finally,a case was illustrated as evi-dence.Results(1)A total of 822 medical records were included in this study,involving 7 gastrointestinal cancers,5 syn-dromes,5 therapies,822 prescriptions,and 215 medicines.(2)25 medicines were used with the frequency above 100,and 75 medicines were used with the dose above 30 g.The mining yielded 7 high-frequency medicine pairs and 5 medicine clusters.Conclusion The mining results reveal Professor He Ren's academic thought and medication characteristics of re-inforcing healthy qi throughout the treatment process,eliminating the pathogen at right time,and treating based on syndrome differentiation in the treatment of gastrointestinal cancer patients.The findings provide a scientific basis for revealing the medication rules and inheriting the academic thought of Professor He Ren.
HE RenGastrointestinal CancerData MiningMedication Rules