首页|国医大师晁恩祥治疗哮喘的用药规律及疏风通络止痉法的应用

国医大师晁恩祥治疗哮喘的用药规律及疏风通络止痉法的应用

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目的 基于网络数据挖掘探析国医大师晁恩祥教授治疗支气管哮喘的组方规律,并对组方经验及疏风通络止痉法的应用进行阐述,以期为临床支气管哮喘的治疗提供思路与指导.方法 收集晁恩祥教授的相关经验书籍及临床典型医案,建立处方数据库,运用古今医案云平台、SPSS Molder 18.0、Cytoscape 2.7.2等统计学软件进行频次分析、关联分析、聚类分析等多元化分析.结果 共收集处方295首,高频药物有杏仁、麻黄、五味子等;药物归经以肺经频次最高,脾经、胃经、心经次之,五味以辛味最高,甘味、苦味次之,四气以温性最高,系统聚类分析得出5个聚类药组,关联分析发现麻黄-杏仁的关联性最强,核心药物分析发现了以杏仁、五味子、麻黄、浙贝母、紫苏子、地龙为主的核心药物组.结论 晁恩祥教授针对在哮喘治疗中常以风药调节体内外气机,配伍上善用"麻黄-地龙"以疏风解痉,通窍降气治其本源,形成了独特的以疏风通络止痉法为中心的治疗体系,可有效指导临床用药.
Medication Rules of TCM Master CHAO Enxiang against Asthma and the Applica-tion of Wind-dispelling,Collateral-dredging,and Spasm-relieving Therapies
Objective To explore the prescription patterns of Professor Chao Enxiang,a traditional Chinese medi-cine(TCM)master,in treating bronchial asthma using network data mining and elucidate his prescription experience and the application of wind-dispelling,collateral-dredging,and spasm-relieving therapies,aiming to provide insights and guidance for the clinical treatment of bronchial asthma.Methods Relevant books detailing Professor Chao's clinical expe-rience and typical medical cases were collected to establish a prescription database.Statistical software,including the Ancient and Modern Medical Records Cloud Platform,SPSS Modeler 18.0,and Cytoscape 2.7.2,was used to perform fre-quency analysis,association analysis,and cluster analysis.Results A total of 295 prescriptions were collected.High-fre-quency herbs included Armeniacae Semen Amarum,Ephedrae Herba,and Schisandrae Chinensis Fructus.The meridian tropism analysis revealed that most drugs targeted the lung meridian,followed by the spleen,stomach,and heart meridians.In terms of flavor,pungency was most frequent,followed by sweet and bitter flavors.Regarding properties,warm drugs were predominant.Cluster analysis identified five drug groups,and association analysis showed the strongest correlation between Ephedrae Herba and Armeniacae Semen Amarum.Core drug analysis highlighted a group of key drugs,including Armenia-cae Semen Amarum,Schisandrae Chinensis Fructus,Ephedrae Herba,Fritillariae Thunbergii Bulbus,Perillae Fructus,and Pheretima.Conclusion Professor Chao Enxiang frequently used wind-dispelling drugs to regulate internal and external qi in the treatment of asthma.He skillfully combined Ephedrae Herba and Pheretima to dispel wind,relieve spasms,un-block orifices,and descend qi,addressing the root cause of the disease.This unique treatment approach,centered on the wind-dispelling,collateral-dredging,and spasm-relieving therapies,offers effective guidance for clinical medication.

CHAO EnxiangAsthmaMedication RuleWind-dispelling,Collateral-dredging,and Spasm-re-lieving Therapies

李家翔、张洪春、晁燕、耿立梅、宿英豪、聂佳、于向艳

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河北中医药大学研究生学院,河北石家庄 050091

中日友好医院,北京 100029

北京东方运嘉科技发展有限公司,北京 100029

河北省中医院呼吸科,河北石家庄 050011

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晁恩祥 哮喘 用药规律 疏风通络止痉法

2024

世界中西医结合杂志
中华中医药学会

世界中西医结合杂志

CSTPCD
影响因子:1.053
ISSN:1673-6613
年,卷(期):2024.19(11)